# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA701213 | Functional | Evaluated for K-ATP activity in terms of change in membrane potential through guinea pig bladder assay | Cavia porcellus | 68 | ALA1148324 | cell membrane format | Scientific Literature | |
2. | ALA701216 | Functional | Evaluated for K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay | Sus scrofa | 36 | ALA1148324 | assay format | Scientific Literature | |
3. | ALA699663 | Functional | Evaluated for K-ATP activity as in vitro bladder relaxation in spontaneous Landrace pig detrusor strips (SLPD) | Sus scrofa | 6 | ALA1148324 | assay format | Scientific Literature | |
4. | ALA848710 | Functional | Selectivity ratio of MAP ED20/bladder ED50 | 3 | ALA1132984 | assay format | Scientific Literature | ||
5. | ALA848711 | Functional | Selectivity ratio of MAP ED20/bladder ED50 | 4 | ALA1132985 | assay format | Scientific Literature | ||
6. | ALA849847 | Functional | Selectivity ratio for the reduction of mean arterial pressure to that of unstable concentration in anesthetized obstructed male rat | 3 | ALA1136389 | tissue-based format | Scientific Literature | ||
7. | ALA846990 | Functional | Selectivity expressed as the ratio of pEC50 (SLPD) and pEC50 (FSLPD) | 6 | ALA1148324 | assay format | Scientific Literature | ||
8. | ALA908895 | Functional | Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay | Homo sapiens | 78 | ALA1137338 | cell-based format | Scientific Literature | |
9. | ALA908896 | Functional | Ability to open human urinary bladder Kir6.2 containing SUR2B in Ltk cells by FLIPR assay relative to P1075 | Homo sapiens | 71 | ALA1137338 | cell-based format | Scientific Literature | |
10. | ALA908308 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusor | Sus scrofa | 22 | ALA1137338 | assay format | Scientific Literature | |
11. | ALA908306 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction | Sus scrofa | 11 | ALA1137338 | assay format | Scientific Literature | |
12. | ALA907148 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusor relative to P1075 | Sus scrofa | 22 | ALA1137338 | assay format | Scientific Literature | |
13. | ALA907149 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction relative to P1075 | Sus scrofa | 11 | ALA1137338 | assay format | Scientific Literature | |
14. | ALA780594 | Functional | Effective dose in vivo for reduction in the frequency of spontaneous bladder contractions in the rat oral administration | Rattus norvegicus | 3 | ALA1132984 | organism-based format | Scientific Literature | |
15. | ALA779561 | Functional | In vitro inhibitory concentration for 50% relaxant effect was measured on rat bladder strips | Rattus norvegicus | 2 | ALA1134478 | organism-based format | Scientific Literature | |
16. | ALA779563 | Functional | In vitro inhibitory concentration that relaxed KCL induced contraction in rat detrusor strip by 50% | Rattus norvegicus | 77 | ALA1132985 | organism-based format | Scientific Literature | |
17. | ALA779564 | Functional | In vitro inhibitory concentration that relaxes KCL induced contraction in rat detrusor strips by 50% | Rattus norvegicus | 76 | ALA1132984 | organism-based format | Scientific Literature | |
18. | ALA783034 | Functional | In vivo concentration required for the inhibition of unstable contraction in anesthetized obstructed male rat, administered intravenously at a dose of 30 nM/Kg | Rattus norvegicus | 3 | ALA1136389 | organism-based format | Scientific Literature | |
19. | ALA785427 | Functional | Compound was evaluated in vivo for the effective dose that cause a 50% reduction in frequency of spontaneous bladder contraction in the rat hypertrophied model after oral administration | Rattus norvegicus | 8 | ALA1132985 | organism-based format | Scientific Literature | |
20. | ALA778525 | Functional | In vivo concentration required for the reduction of mean arterial pressure in anesthetized obstructed male rat, administered intravenously at a dose of 50 nM/Kg | Rattus norvegicus | 2 | ALA1136389 | organism-based format | Scientific Literature |