# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2066745 | F | Antiinflammatory activity against LPS-induced NO production in mouse RAW264.7 cells assessed as reduction in nitrite level at 50 uM preincubated for 15 mins prior to LPS treatment by Griess method | Mus musculus | 9 | ALA2062500 | cell-based format | Scientific Literature | |
2. | ALA2066746 | A | Cytotoxicity in mouse RAW264.7 cells assessed as cell survival at 50 uM | Mus musculus | 9 | ALA2062500 | cell-based format | Scientific Literature | |
3. | ALA2066747 | F | Antiinflammatory activity against LPS-induced NO production in mouse RAW264.7 cells assessed as reduction in nitrite level preincubated for 15 mins prior to LPS treatment by Griess method | Mus musculus | 10 | ALA2062500 | cell-based format | Scientific Literature | |
4. | ALA2066748 | B | Inhibition of TNFalpha-induced NF-kappaB activity expressed in human HEK 293 cells at 50 uM after 6 hrs by luciferase reporter gene assay | Homo sapiens | 9 | ALA2062500 | cell-based format | Scientific Literature | |
5. | ALA2066749 | A | Cytotoxicity in human HEK293 cells assessed as survival at 50 uM | Homo sapiens | 9 | ALA2062500 | cell-based format | Scientific Literature | |
6. | ALA2066750 | B | Inhibition of TNFalpha-induced NF-kappaB activity expressed in human HEK 293 cells after 6 hrs by luciferase reporter gene assay | Homo sapiens | 11 | ALA2062500 | cell-based format | Scientific Literature | |
7. | ALA3632013 | B | Inhibition of Stat3 dimer DNA binding activity in mouse NIH3T3/vSrc nuclear extract at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe hSIE for 30 mins by EMSA | Mus musculus | 24 | ALA3627612 | single protein format | Scientific Literature | |
8. | ALA3632017 | B | Inhibition of Stat5 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear extract expressing human EGFR at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe MGFe for 30 mins by EMSA | Mus musculus | 11 | ALA3627612 | cell-based format | Scientific Literature | |
9. | ALA3632018 | B | Inhibition of Stat1 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear extract expressing human EGFR at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe hSIE for 30 mins by EMSA | Mus musculus | 12 | ALA3627612 | single protein format | Scientific Literature | |
10. | ALA3632022 | B | Inhibition of Stat3 activity in human U251MG cells assessed as phosphorylated Stat3 level at 5 uM by immunoblot analysis | Homo sapiens | 5 | ALA3627612 | cell-based format | Scientific Literature | |
11. | ALA3632151 | B | Binding affinity to Stat3 (unknown origin) by NMR analysis | Homo sapiens | 5 | ALA3627612 | single protein format | Scientific Literature | |
12. | ALA3632157 | F | Antiproliferative activity against human U251MG cells for 72 hrs by cyquant assay | Homo sapiens | 9 | ALA3627612 | cell-based format | Scientific Literature | |
13. | ALA3632158 | F | Antiproliferative activity against human MDA-MB-231 cells for 72 hrs by cyquant assay | Homo sapiens | 5 | ALA3627612 | cell-based format | Scientific Literature | |
14. | ALA3632159 | F | Antiproliferative activity against human U373MG cells for 72 hrs by cyquant assay | Homo sapiens | 5 | ALA3627612 | cell-based format | Scientific Literature | |
15. | ALA3632160 | F | Antiproliferative activity against human SF295 cells for 72 hrs by cyquant assay | Homo sapiens | 5 | ALA3627612 | cell-based format | Scientific Literature | |
16. | ALA3630072 | F | Antiproliferative activity against human MCF7 cells for 72 hrs by cyquant assay | Homo sapiens | 5 | ALA3627612 | cell-based format | Scientific Literature | |
17. | ALA3630073 | A | Cytotoxicity against mouse NIH/3T3 cells after 72 hrs by cyquant cells | Mus musculus | 9 | ALA3627612 | cell-based format | Scientific Literature | |
18. | ALA3630077 | F | Antiproliferative activity against human U251MG cells at 5 uM for 72 hrs by cyquant assay | Homo sapiens | 25 | ALA3627612 | cell-based format | Scientific Literature | |
19. | ALA3630188 | F | Antiproliferative activity against human MDA-MB-231 cells at 5 uM for 72 hrs by cyquant assay | Homo sapiens | 19 | ALA3627612 | cell-based format | Scientific Literature | |
20. | ALA3630189 | F | Antiproliferative activity against human SF295 cells at 5 uM for 72 hrs by cyquant assay | Homo sapiens | 15 | ALA3627612 | cell-based format | Scientific Literature |