# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2066208 | B | Inhibition of SMO expressed in mouse C3H10T1/2 cells assessed as down-regulation of Gli1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to oxysterol | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
2. | ALA2066209 | A | Binding affinity to full length human VDR by fluorescence polarization-based competitive assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
3. | ALA2066210 | A | Binding affinity to full length human VDR expressed in mouse C3H10T1/2 cells assessed as upregulation of CYP24A1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
4. | ALA2066211 | F | Growth inhibition of human U87MG cells after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
5. | ALA2066212 | F | Growth inhibition of human HT-29 cells overexpressing VDR gene after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
6. | ALA2066213 | F | Down-regulation of Gli1 mRNA expression in human U87MG cells at 10 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
7. | ALA2066214 | F | Upregulation of CYP24A1 mRNA expression in human U87MG cells at 10 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
8. | ALA2066215 | F | Down-regulation of Gli1 mRNA expression in human HT-29 cells at 10 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
9. | ALA2066216 | F | Upregulation of CYP24A1 mRNA expression in human HT-29 cells at 10 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
10. | ALA2411988 | B | Inhibition of Hedgehog signaling in mouse ASZ001 cells assessed as downregulation of Gli1 mRNA expression at 10 uM after 48 hrs by RT-PCR analysis relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA2411991 | B | Activation of VDR in human DaOY cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 48 hrs by RT-PCR analysis relative to DMSO-treated control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
12. | ALA2411992 | B | Inhibition of Hedgehog signaling in human DaOY cells assessed as downregulation of Gli1 mRNA expression after 48 hrs by RT-PCR analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
13. | ALA2411993 | B | Activation of VDR in mouse ASZ001 cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 48 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 6 | cell-based format | Scientific Literature | ||
14. | ALA2411995 | B | Inhibition of Hedgehog signaling in mouse ASZ001 cells assessed as downregulation of Gli1 mRNA expression after 48 hrs by RT-PCR analysis | Mus musculus | 7 | cell-based format | Scientific Literature | ||
15. | ALA2412000 | B | Inhibition of Hedgehog signaling in mouse M210B4 cells assessed as downregulation of Ptch mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
16. | ALA2412001 | B | Inhibition of Hedgehog signaling in mouse M210B4 cells assessed as downregulation of Gli1 mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
17. | ALA2412002 | B | Inhibition of Hedgehog signaling in mouse C3H10T1/2 cells assessed as downregulation of Ptch mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
18. | ALA2412003 | B | Inhibition of Hedgehog signaling in mouse C3H10T1/2 cells assessed as downregulation of Gli1 mRNA expression after 24 hrs by RT-PCR analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
19. | ALA2412619 | B | Binding affinity to human VDR by fluorescence polarization assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
20. | ALA2412620 | B | Activation of VDR in mouse C3H10T1/2 cells assessed as upregulation of Cyp24A1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to DMSO-treated control | Mus musculus | 12 | cell-based format | Scientific Literature |