# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2067493 | B | Displacement of [3H]R-PIA from human recombinant adenosine A1 receptor expressed in CHO cells at 10 uM after 60 mins by liquid scintillation counting | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
2. | ALA2067495 | B | Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
3. | ALA2067496 | B | Displacement of [3H]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
4. | ALA2067498 | F | Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM incubated for 30 mins prior to forskolin-stimulation measured after 15 mins by enzyme immunoassay relative to NECA | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
5. | ALA3413614 | B | Displacement of [3H]R-PIA from human recombinant A1 adenosine receptor expressed in CHO cells at 10 uM after 60 mins by liquid scintillation counting | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
6. | ALA3413615 | B | Displacement of [3H]CGS21680 from human recombinant A2A adenosine receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
7. | ALA3413616 | B | Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
8. | ALA3413619 | B | Displacement of [125I]I-AB-MECA from mouse A3 adenosine receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting | Mus musculus | 14 | cell-based format | Scientific Literature | ||
9. | ALA3413620 | F | Antinociceptive activity in chronic constriction injury neutropathic pain CD-1 mouse model assessed as time for peak protection at 3 umol/kg, po | Mus musculus | 35 | organism-based format | Scientific Literature | ||
10. | ALA3413621 | F | Antinociceptive activity in chronic constriction injury neutropathic pain CD-1 mouse model assessed as maximum protection on ipsilateral hind paw at 3 umol/kg, po after 30 mins to 5 hrs post dose relative to control | Mus musculus | 35 | organism-based format | Scientific Literature | ||
11. | ALA3413622 | F | Antinociceptive activity in chronic constriction injury neutropathic pain CD-1 mouse model at 3 umol/kg, po after 3 hrs post dose relative to control | Mus musculus | 35 | organism-based format | Scientific Literature | ||
12. | ALA3414372 | B | Selectivity ratio of Ki for mouse A3 adenosine receptor expressed in HEK293 cells to Ki for human recombinant A3 adenosine receptor expressed in CHO cells | 12 | cell-based format | Scientific Literature | |||
13. | ALA3414402 | B | Inhibition of human ERG by PDSP screening | Homo sapiens | 4 | single protein format | Scientific Literature | ||
14. | ALA3414403 | B | Selectivity ratio of IC50 for human ERG to IC50 for human recombinant A3 adenosine receptor expressed in CHO cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
15. | ALA4011340 | B | Enhancing of [125I]RTI-55 binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
16. | ALA4011341 | B | Enhancing of [3H]mazindol binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
17. | ALA4011342 | B | Enhancing of [125I]RTI-55 binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
18. | ALA4011343 | B | Inhibition of recombinant human DAT expressed in HEK293 cell membranes assessed as reduction in [3H]-DA uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
19. | ALA4011344 | B | Enhancing of [3H]mazindol binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
20. | ALA4011345 | B | Inhibition of recombinant human NET expressed in HEK293 cell membranes assessed as reduction in [3H]-norepinephrine uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | cell-based format | Scientific Literature |