| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2072489 | B | Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation counting | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 2. | ALA2072490 | F | Antagonist activity at human SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated for 15 mins before SS-14 challenge measured after 1 hr by time-resolved fluorescence analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 3. | ALA2072491 | B | Displacement of [35S]MK499 from human Erg expressed in HEK293 cells after 60 mins by scintillation counting | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA2072502 | B | Binding affinity to L-type calcium channel | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 5. | ALA2072503 | A | Dose normalized AUC in C57BL/6N mouse at 2 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA2072504 | A | Cmax in C57BL/6N mouse at 2 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA2072505 | A | Volume of distribution at steady state in C57BL/6N mouse at 1 mg/kg, iv and 2 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA2072506 | A | Clearance in C57BL/6N mouse at 1 mg/kg, iv and 2 mg/kg, po | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA2072507 | A | Half life in C57BL/6N mouse at 1 mg/kg, iv and 2 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA2072508 | A | Oral bioavailability in C57BL/6N mouse at 2 mg/kg | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA2072626 | B | Binding affinity to human SST3 receptor | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA2072627 | B | Selectivity for human SST3 receptor over human SST1 receptor | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 13. | ALA2072628 | B | Selectivity for human SST3 receptor over human SST2 receptor | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 14. | ALA2072629 | B | Selectivity for human SST3 receptor over human SST4 receptor | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 15. | ALA2072630 | B | Selectivity for human SST3 receptor over human SST5 receptor | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 16. | ALA3583381 | B | Displacement of [125I]SS-14 from human recombinant SSTR3 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
| 17. | ALA3583382 | F | Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence of SS-14 by time-resolved fluorescence assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
| 18. | ALA3583383 | B | Inhibition of MK499 binding to human ERG | Homo sapiens | 42 | single protein format | Scientific Literature |
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