# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA640467 | B | Ability to displace radioligand [3H]- DPCPX from adenosine A1 receptor on rat cortical membrane in the absence of GTP | 14 | assay format | Scientific Literature | |||
2. | ALA640468 | B | Ability to displace radioligand [3H]- DPCPX from adenosine A1 receptor on rat cortical membrane in the presence of 1 mM of GTP | 13 | assay format | Scientific Literature | |||
3. | ALA641310 | B | Ability to displace radioligand [3H]- CGS 21680 from adenosine A2A receptor on rat striatal membrane | 15 | assay format | Scientific Literature | |||
4. | ALA639461 | F | Effective concentration for cAMP production in CHO-KI cells stably transfected with human adenosine A2B receptor cDNA | 14 | cell-based format | Scientific Literature | |||
5. | ALA646602 | B | Ability to displace radioligand [125I]AB-MECA from membrane of HEK 293 cells stably transfected with human adenosine A3 receptor cDNA | 13 | cell-based format | Scientific Literature | |||
6. | ALA667156 | F | Tested for the percent increase in aortic blood pressure (BP) in open chest anesthetized dog at intravenous dosage of 0.01 mg/kg | Canis lupus familiaris | 13 | organism-based format | Scientific Literature | ||
7. | ALA664470 | F | Tested for the percent increase in heart rate (HR) in open chest anesthetized dog at intravenous dosage of 0.01 mg/kg | Canis lupus familiaris | 13 | organism-based format | Scientific Literature | ||
8. | ALA660601 | F | Total time in minutes elapsed from the initiation of the change until return to the pretest value of blood pressure in coronary sinus of anesthetized dog at intravenous dosage of 0.01 mg/kg | Canis lupus familiaris | 12 | organism-based format | Scientific Literature | ||
9. | ALA665392 | F | Total time in minutes elapsed from the initiation of the change until return to the pretest value of heart rate in coronary sinus of anesthetized dog at intravenous dosage of 0.01 mg/kg | Canis lupus familiaris | 12 | organism-based format | Scientific Literature | ||
10. | ALA665403 | F | Total time in minutes elapsed from the initiation of the change until return to the pretest value of oxygen partial pressure in coronary sinus of anesthetized dog at intravenous dosage of 0.01 mg/kg | Canis lupus familiaris | 12 | organism-based format | Scientific Literature | ||
11. | ALA666896 | F | Tested for percent increase in coronary sinus partial pressure of oxygen (PO2) in open chest anesthetized dog at intravenous dosage of 0.01 mg/kg | Canis lupus familiaris | 13 | organism-based format | Scientific Literature | ||
12. | ALA727508 | T | Lethal dose in mice after intraperitoneal administration | Mus musculus | 40 | organism-based format | Scientific Literature | ||
13. | ALA728074 | T | Lethal dose in mice after peroral administration | Mus musculus | 40 | organism-based format | Scientific Literature | ||
14. | ALA754752 | B | Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes | 39 | cell membrane format | Scientific Literature | |||
15. | ALA842883 | B | GTP shift was determined | 13 | assay format | Scientific Literature | |||
16. | ALA2072274 | B | Displacement of 3[H]R-PIA from human A1 adenosine receptor expressed in CHO cells after 60 mins by Liquid scintillation analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
17. | ALA2072275 | B | Displacement of 3[H]CGS21680 from human A2A adenosine receptor expressed in HEK293 cells after 60 mins by Liquid scintillation analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
18. | ALA2072276 | B | Displacement of [125I]I-AB-MECA from human A3 adenosine receptor expressed in CHO cells after 60 mins gamma counter | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
19. | ALA2072277 | B | Displacement of 3[H]R-PIA from rat A1 adenosine receptor expressed in CHO cells after 60 min by Liquid scintillation analysis | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
20. | ALA2072283 | F | Agonist activity at human A2A adenosine receptor expressed in CHO cells assessed as stimulation of forskolin-induced cAMP accumulation after 30 mins relative to NECA | Homo sapiens | 2 | cell-based format | Scientific Literature |