The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2071880 B Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis Homo sapiens 42 single protein format Scientific Literature 2. ALA2071881 B Inhibition of PDE2 Homo sapiens 42 single protein format Scientific Literature 3. ALA2071882 B Inhibition of PDE3 Homo sapiens 35 protein format Scientific Literature 4. ALA2071883 B Inhibition of PDE4 Homo sapiens 35 protein format Scientific Literature 5. ALA2071884 B Inhibition of PDE5 Homo sapiens 35 single protein format Scientific Literature 6. ALA2071885 B Inhibition of PDE6 Homo sapiens 35 protein format Scientific Literature 7. ALA2071896 A Oral bioavailability in rat at 10 mg/kg Rattus norvegicus 4 organism-based format Scientific Literature 8. ALA2071897 A Elimination half life in rat at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 4 organism-based format Scientific Literature 9. ALA2071898 A Clearance in rat at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 4 organism-based format Scientific Literature 10. ALA2071899 A Volume of distribution at steady state in rat at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 4 organism-based format Scientific Literature 11. ALA2071900 A AUC in rat brain at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 4 organism-based format Scientific Literature 12. ALA2071901 A AUC in rat plasma at 2 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 4 organism-based format Scientific Literature 13. ALA2071902 F Antipsychotic activity in po dosed rat assessed as reduction of MK801-induced hyperactivity Rattus norvegicus 7 organism-based format Scientific Literature 14. ALA2071903 F Antipsychotic activity in po dosed rat assessed as reduction of MK801-induced stereotyped sniffing Rattus norvegicus 7 organism-based format Scientific Literature 15. ALA2071904 F Antipsychotic activity in po dosed Sprague-Dawley rat assessed as reduction of conditioned avoidance response Rattus norvegicus 1 organism-based format Scientific Literature 16. ALA2071905 F Antipsychotic activity in Sprague-Dawley rat assessed as reduction of conditioned avoidance response at 0.17 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 17. ALA2187458 B Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation counting 10 cell-based format Scientific Literature 18. ALA2187828 B Inhibition of recombinant PDE2A expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation counting 9 cell-based format Scientific Literature