| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2073358 | T | Cardiotoxicity in dog assessed as increase in heart rate at > 10 times IC50 | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2073612 | A | Clearance in iv dosed rat | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 3. | ALA2073614 | A | Intrinsic clearance in rat liver microsomes | Rattus norvegicus | 18 | microsome format | Scientific Literature | ||
| 4. | ALA2073616 | B | Inhibition of PDE8B expressed in Sf9 insect cells | Homo sapiens | 111 | cell-based format | Scientific Literature | ||
| 5. | ALA2073617 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 25 | microsome format | Scientific Literature | ||
| 6. | ALA2073618 | A | Oral bioavailability in rat | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 7. | ALA2073619 | A | Clearance in iv dosed dog | Canis lupus familiaris | 8 | organism-based format | Scientific Literature | ||
| 8. | ALA2073620 | A | Oral bioavailability in dog | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA2073621 | P | Dissociation constant, pKa of the compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA2073622 | P | Solubility of the compound at pH 7.4 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA2073623 | P | Solubility of the compound at pH 4 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 12. | ALA2073624 | B | Inhibition of PDE8A | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA2073625 | B | Inhibition of PDE | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA2073626 | A | Genotoxicity in micronucleus | 6 | assay format | Scientific Literature | |||
| 15. | ALA2073627 | T | Genotoxicity in Salmonella typhimurium | Salmonella enterica subsp. enterica serovar Typhimurium | 6 | organism-based format | Scientific Literature | ||
| 16. | ALA2073628 | B | Inhibition of kappa opioid receptor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA2073629 | B | Inhibition of human ERG | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA2073630 | A | Efflux ratio of permeability of the compound across MDCK cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA2073631 | A | Fraction unbound in rat plasma | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
| 20. | ALA2073632 | A | Fraction unbound in dog plasma | Canis lupus familiaris | 1 | cell-free format | Scientific Literature |
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