# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2091156 | B | Inhibition of human recombinant TG2 by fluorescent transamidation assay | Homo sapiens | 106 | single protein format | Scientific Literature | ||
2. | ALA2091157 | B | Irreversible inhibition of human recombinant TG2 assessed as ratio of Kinact to Ki | Homo sapiens | 55 | single protein format | Scientific Literature | ||
3. | ALA2091158 | B | Inhibition of human recombinant TG1 by fluorescent transamidation assay | Homo sapiens | 90 | single protein format | Scientific Literature | ||
4. | ALA2091159 | B | Inhibition of thrombin activated human TG3 by fluorescent transamidation assay | Homo sapiens | 69 | single protein format | Scientific Literature | ||
5. | ALA2091160 | B | Inhibition of thrombin activated human F13a by fluorescent transamidation assay | Homo sapiens | 90 | single protein format | Scientific Literature | ||
6. | ALA2091168 | B | Inhibition of human TG2 in HEK cells by fluorescent transamidation assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
7. | ALA2091169 | B | Ratio of IC50 to human TG2 in HEK cells to IC50 for human recombinant TG2 | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
8. | ALA2091170 | P | Kinetic solubility of the compound in phosphate buffered saline at pH 7.4 | 9 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA2091171 | A | Fraction unbound in human plasma at 10 uM after 6 hrs | Homo sapiens | 9 | cell-free format | Scientific Literature | ||
10. | ALA2091172 | A | Apparent permeability from apical to basolateral side in human Caco2 cells after 1 hr | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
11. | ALA2091173 | A | Apparent permeability from basolateral side to apical side in human Caco2 cells after 1 hr | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
12. | ALA2091213 | A | Half life in mouse plasma at 1 uM | Mus musculus | 9 | cell-free format | Scientific Literature | ||
13. | ALA2091214 | A | Intrinsic clearance in mouse liver microsomes at 1 uM | Mus musculus | 9 | microsome format | Scientific Literature |