| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2091156 | B | Inhibition of human recombinant TG2 by fluorescent transamidation assay | Homo sapiens | 106 | single protein format | Scientific Literature | ||
| 2. | ALA2091158 | B | Inhibition of human recombinant TG1 by fluorescent transamidation assay | Homo sapiens | 90 | single protein format | Scientific Literature | ||
| 3. | ALA2091159 | B | Inhibition of thrombin activated human TG3 by fluorescent transamidation assay | Homo sapiens | 69 | single protein format | Scientific Literature | ||
| 4. | ALA2091160 | B | Inhibition of thrombin activated human F13a by fluorescent transamidation assay | Homo sapiens | 90 | single protein format | Scientific Literature | ||
| 5. | ALA2091161 | B | Selectivity ratio of IC50 for human F13a to IC50 for human recombinant TG2 | Homo sapiens | 11 | assay format | Scientific Literature | ||
| 6. | ALA2091163 | B | Selectivity ratio of IC50 for human recombinant TG1 to IC50 for human recombinant TG2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA2091164 | B | Selectivity ratio of IC50 for human recombinant TG3 to IC50 for human TG2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA2091165 | B | Selectivity ratio of IC50 for human recombinant TG6 to IC50 for human recombinant TG2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA2091166 | B | Inhibition of human recombinant TG6 by fluorescent transamidation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2091167 | B | Inhibition of mouse recombinant TG2 by fluorescent transamidation assay | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2091168 | B | Inhibition of human TG2 in HEK cells by fluorescent transamidation assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 12. | ALA2091169 | B | Ratio of IC50 to human TG2 in HEK cells to IC50 for human recombinant TG2 | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 13. | ALA2091170 | P | Kinetic solubility of the compound in phosphate buffered saline at pH 7.4 | 9 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA2091171 | A | Fraction unbound in human plasma at 10 uM after 6 hrs | Homo sapiens | 9 | cell-free format | Scientific Literature | ||
| 15. | ALA2091172 | A | Apparent permeability from apical to basolateral side in human Caco2 cells after 1 hr | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 16. | ALA2091173 | A | Apparent permeability from basolateral side to apical side in human Caco2 cells after 1 hr | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 17. | ALA2091213 | A | Half life in mouse plasma at 1 uM | Mus musculus | 9 | cell-free format | Scientific Literature | ||
| 18. | ALA2091214 | A | Intrinsic clearance in mouse liver microsomes at 1 uM | Mus musculus | 9 | microsome format | Scientific Literature | ||
| 19. | ALA5225353 | B | Inhibition of TG2 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!