# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2091217 | B | Displacement of [125I]Ang 2 from rat liver membrane AT1 receptor after 2 hrs by micro-counter | Rattus norvegicus | 41 | assay format | Scientific Literature | ||
2. | ALA2091218 | B | Displacement of [125I]Ang 2 from pig uterus membrane AT2 receptor after 1.5 hrs by micro-counter | Sus scrofa | 41 | assay format | Scientific Literature | ||
3. | ALA2091219 | F | Induction of neurite outgrowth in mouse/rat NG108-15 cells at 10 nM after 3 days by phase contrast microscopy | 3 | cell-based format | Scientific Literature | |||
4. | ALA2091220 | F | Inhibition of Ang 2-induced neurite outgrowth in mouse/rat NG108-15 cells at 10 nM after 3 days by phase contrast microscopy (Rvb = 17.5 %) | 1 | cell-based format | Scientific Literature | |||
5. | ALA3385517 | B | Binding affinity to AT1 receptor (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA3385518 | B | Binding affinity to AT2 receptor (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
7. | ALA3396449 | B | Displacement of [125I]-Ang II from AT1 receptor in rat liver membranes after 2 hrs by gamma-counting method | Rattus norvegicus | 2 | cell membrane format | Scientific Literature | ||
8. | ALA3396450 | B | Displacement of [125I]-Ang II from AT2 receptor in pig uterus myometrial membranes after 1.5 hrs by gamma-counting method | Sus scrofa | 6 | cell membrane format | Scientific Literature | ||
9. | ALA3768050 | B | Displacement of 125I-[Sar1,Leu8] angiotensin-2 from rat type 1 angiotensin-2 receptor expressed in African green monkey COS7 cells after 24 hrs | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
10. | ALA3768051 | B | Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Homo sapiens | 12 | single protein format | Scientific Literature | ||
11. | ALA4184605 | A | Half life in mouse liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Mus musculus | 19 | microsome format | Scientific Literature | ||
12. | ALA4184606 | A | Half life in human liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 19 | microsome format | Scientific Literature | ||
13. | ALA4184607 | B | Displacement of [Sar1-Ile5-Ile8]-Ang2 from Type-2 angiotensin 2 receptor AT2 in pig uterus myometrium membranes by gamma counting analysis | Sus scrofa | 1 | cell membrane format | Scientific Literature | ||
14. | ALA4184608 | B | Displacement of [125I][Sar1,Ile8]-angiotensin-2 from human recombinant AT2 receptor expressed in HEK293 cell membranes after 240 mins by scintillation counting | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
15. | ALA4184609 | B | Displacement of [125I][Sar1,Ile8]-AT-II from human recombinant AT1 at 10 uM after 120 mins by scintillation counting analysis relative to control | Homo sapiens | 19 | single protein format | Scientific Literature | ||
16. | ALA4678991 | B | Displacement of [125I]Sar-Ile-angiotensin 2 from human AT2 receptor expressed in HEK293 cells incubated for 240 mins by radiometric scintillation analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
17. | ALA4678993 | A | Half life in mouse liver microsomes at 1 uM measured up to 60 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 20 | microsome format | Scientific Literature | ||
18. | ALA4678994 | A | Half life in human liver microsomes at 1 uM measured up to 60 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 20 | microsome format | Scientific Literature | ||
19. | ALA4678995 | A | Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 3 mins followed by NADPH addition by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
20. | ALA4678996 | A | Apparent permeability across apical to basolateral side and basolateral to apical side in human Caco-2 cells at 5 uM measured up to 60 mins by LC-MS/MS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |