# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2089417 | F | Antagonist activity at human CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulation | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA2089418 | F | Antagonist activity at human CRF2 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2089419 | F | Anxiolytic activity against BALB/c mouse assessed as increase in time spent in light box at 10 mg/kg, po after 1 hr by light/dark test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA2089420 | F | Anxiolytic activity against BALB/c mouse assessed as increase in number of crosses at 10 mg/kg, po after 1 hr by light/dark test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2089421 | A | Clearance in CD1 (ICR) mouse at 3 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2089422 | A | Volume of distribution at steady state in CD1 (ICR) mouse 3 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2089423 | A | AUC in CD1 (ICR) mouse at 3 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2089424 | A | Terminal half life in CD1 (ICR) mouse at 3 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2089425 | A | Cmax in CD1 (ICR) mouse at 10 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2089426 | A | Tmax in CD1 (ICR) mouse 10 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA2089427 | A | AUC in CD1 (ICR) mouse at 10 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA2089428 | A | Oral bioavailability in CD1 (ICR) mouse at 10 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA2089429 | B | Activity at human P-gp at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA2089430 | B | Inhibition of human ERG channel | Homo sapiens | 1 | single protein format | Scientific Literature |