# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2092446 | Binding | Inhibition of p38alpha | 36 | ALA2086331 | single protein format | Scientific Literature | ||
2. | ALA2092447 | Functional | Inhibition of LPS-induced TNFalpha production in human whole blood | Homo sapiens | 33 | ALA2086331 | tissue-based format | Scientific Literature | |
3. | ALA2092448 | ADME | Stability in rat hepatic microsomes assessed as compound turnover at 5 uM incubated for 30 mins in presence of NADPH | Rattus norvegicus | 3 | ALA2086331 | microsome format | Scientific Literature | |
4. | ALA2092449 | ADME | Stability in human hepatic microsomes assessed as compound turnover at 5 uM incubated for 30 mins in presence of NADPH | Homo sapiens | 3 | ALA2086331 | microsome format | Scientific Literature | |
5. | ALA2092450 | ADME | Passive permeability from apical to basolateral side in human Caco2 cells at 12.5 uM | Homo sapiens | 3 | ALA2086331 | cell-based format | Scientific Literature | |
6. | ALA2092451 | ADME | Passive permeability from basolateral to apical side in human Caco2 cells at 12.5 uM | Homo sapiens | 3 | ALA2086331 | cell-based format | Scientific Literature | |
7. | ALA2092453 | ADME | Cytotoxicity against CHO cells at 200 uM | Cricetulus griseus | 2 | ALA2086331 | cell-based format | Scientific Literature | |
8. | ALA2092454 | ADME | Protein binding in rat plasma | Rattus norvegicus | 3 | ALA2086331 | cell-free format | Scientific Literature | |
9. | ALA2092455 | ADME | Protein binding in human plasma | Homo sapiens | 3 | ALA2086331 | cell-free format | Scientific Literature | |
10. | ALA2092456 | ADME | Half life in Wistar rat at 1 mg/kg, iv | Rattus norvegicus | 3 | ALA2086331 | organism-based format | Scientific Literature | |
11. | ALA2092457 | ADME | AUC in Wistar rat at 1 mg/kg, iv | Rattus norvegicus | 3 | ALA2086331 | organism-based format | Scientific Literature | |
12. | ALA2092458 | ADME | Clearance in Wistar rat at 1 mg/kg, iv | Rattus norvegicus | 3 | ALA2086331 | organism-based format | Scientific Literature | |
13. | ALA2092459 | ADME | Volume of distribution at steady state in Wistar rat at 1 mg/kg, iv | Rattus norvegicus | 3 | ALA2086331 | organism-based format | Scientific Literature | |
14. | ALA2092460 | ADME | Cmax in Wistar rat at 10 mg/kg, po | Rattus norvegicus | 3 | ALA2086331 | organism-based format | Scientific Literature | |
15. | ALA2092461 | ADME | AUC in Wistar rat at 10 mg/kg, po | Rattus norvegicus | 3 | ALA2086331 | organism-based format | Scientific Literature | |
16. | ALA2092462 | ADME | Oral bioavailability in Wistar rat at 10 mg/kg | Rattus norvegicus | 3 | ALA2086331 | organism-based format | Scientific Literature | |
17. | ALA2092463 | ADME | AUC in beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 3 | ALA2086331 | organism-based format | Scientific Literature | |
18. | ALA2092464 | ADME | Clearance in beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 3 | ALA2086331 | organism-based format | Scientific Literature | |
19. | ALA2092465 | ADME | Volume of distribution at steady state in beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 3 | ALA2086331 | organism-based format | Scientific Literature | |
20. | ALA2092466 | ADME | Cmax in beagle dog at 1 mg/kg, po | Canis lupus familiaris | 2 | ALA2086331 | organism-based format | Scientific Literature |