| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2091129 | B | Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay | Homo sapiens | 36 | assay format | Scientific Literature | ||
| 2. | ALA2091130 | B | Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 3. | ALA2091174 | B | Inhibition of ALK5 activity in mouse NMuMG cells assessed as TGFbeta-induced phosphorylation of Smad2 at 0.1 to 0.5 uM after 1 hr by Western blot analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA2091175 | B | Inhibition of human ALK5 activity in human HaCaT cells expressing p3TP-luciferase reporter construct assessed as TGFbeta-induced p3TP-luciferase reporter activity at 30 nM relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 5. | ALA2091176 | B | Selectivity index, ratio of IC50 for human recombinant p38alpha to IC50 for human recombinant ALK5 | Homo sapiens | 36 | assay format | Scientific Literature |
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