# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2090336 | B | Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Mus musculus | 20 | single protein format | Scientific Literature | ||
2. | ALA2090337 | B | Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Mus musculus | 20 | single protein format | Scientific Literature | ||
3. | ALA2090338 | B | Selectivity ratio of IC50 for mouse p38beta to IC50 for mouse p38alpha | Mus musculus | 20 | assay format | Scientific Literature | ||
4. | ALA2090339 | F | Inhibition of LPS-induced TNFalpha production in human THP1 cells pre-incubated for before LPS challenge and measured 4 hrs post LPS challenge by ELISA | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
5. | ALA2090340 | F | Inhibition of LPS-induced TNFalpha production in human whole blood pre-incubated for before LPS challenge and measured 4 hrs post LPS challenge by ELISA | Homo sapiens | 19 | tissue-based format | Scientific Literature | ||
6. | ALA2090341 | B | Activation of PXR | 4 | single protein format | Scientific Literature | |||
7. | ALA2090343 | A | Half life in rat at 1 mg/kg, iv or 2 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
8. | ALA2090346 | A | Clearance in rat at 1 mg/kg, iv or 2 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
9. | ALA2090349 | A | AUC in rat at 1 mg/kg, iv or 2 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
10. | ALA2090352 | A | Oral bioavailability in rat at 2 mg/kg | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
11. | ALA2090355 | F | Reduction in LPS-induced TNFalpha level in rat arthritic model at 3 mg/kg, po measured 4 hrs post dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
12. | ALA2090356 | F | Reduction in LPS-induced TNFalpha level in rat arthritic model at 3 mg/kg, po measured 24 hrs post dose | Rattus norvegicus | 3 | organism-based format | Scientific Literature |