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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2090336 B Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay Mus musculus 20 single protein format Scientific Literature 2. ALA2090337 B Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay Mus musculus 20 single protein format Scientific Literature 3. ALA2090338 B Selectivity ratio of IC50 for mouse p38beta to IC50 for mouse p38alpha Mus musculus 20 assay format Scientific Literature 4. ALA2090339 F Inhibition of LPS-induced TNFalpha production in human THP1 cells pre-incubated for before LPS challenge and measured 4 hrs post LPS challenge by ELISA Homo sapiens 20 cell-based format Scientific Literature 5. ALA2090340 F Inhibition of LPS-induced TNFalpha production in human whole blood pre-incubated for before LPS challenge and measured 4 hrs post LPS challenge by ELISA Homo sapiens 19 tissue-based format Scientific Literature 6. ALA2090342 F Potency shift, ratio of EC50 for LPS-induced TNFalpha production in human whole blood to IC50 for mouse p38apha 2 tissue-based format Scientific Literature 7. ALA2090343 A Half life in rat at 1 mg/kg, iv or 2 mg/kg, po Rattus norvegicus 3 organism-based format Scientific Literature 8. ALA2090344 A Half life in dog at 0.25 mg/kg, iv or 2 mg/kg, po Canis lupus familiaris 2 organism-based format Scientific Literature 9. ALA2090345 A Half life in monkey at 1 mg/kg, iv or 2 mg/kg, po Macaca mulatta 2 organism-based format Scientific Literature 10. ALA2090346 A Clearance in rat at 1 mg/kg, iv or 2 mg/kg, po Rattus norvegicus 3 organism-based format Scientific Literature 11. ALA2090347 A Clearance in dog at 0.25 mg/kg, iv or 2 mg/kg, po Canis lupus familiaris 2 organism-based format Scientific Literature 12. ALA2090348 A Clearance in monkey at 1 mg/kg, iv or 2 mg/kg, po Macaca mulatta 2 organism-based format Scientific Literature 13. ALA2090349 A AUC in rat at 1 mg/kg, iv or 2 mg/kg, po Rattus norvegicus 3 organism-based format Scientific Literature 14. ALA2090350 A AUC in dog at 0.25 mg/kg, iv or 2 mg/kg, po Canis lupus familiaris 2 organism-based format Scientific Literature 15. ALA2090351 A AUC in monkey at 1 mg/kg, iv or 2 mg/kg, po Macaca mulatta 2 organism-based format Scientific Literature 16. ALA2090352 A Oral bioavailability in rat at 2 mg/kg Rattus norvegicus 3 organism-based format Scientific Literature 17. ALA2090353 A Oral bioavailability in dog at 2 mg/kg Canis lupus familiaris 2 organism-based format Scientific Literature 18. ALA2090354 A Oral bioavailability in monkey at 2 mg/kg Macaca mulatta 2 organism-based format Scientific Literature 19. ALA2090355 F Reduction in LPS-induced TNFalpha level in rat arthritic model at 3 mg/kg, po measured 4 hrs post dose Rattus norvegicus 2 organism-based format Scientific Literature 20. ALA2090356 F Reduction in LPS-induced TNFalpha level in rat arthritic model at 3 mg/kg, po measured 24 hrs post dose Rattus norvegicus 3 organism-based format Scientific Literature