| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2098495 | F | GSK_TB: Intracellular minimum inhibitory concentration (MIC) BCG assay | Mycobacterium tuberculosis variant bovis BCG | 776 | organism-based format | GSK Tuberculosis Screening | ||
| 2. | ALA4384517 | B | Inhibition of human AC1 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A23187 stimulation and measured after 1 hr by fluorescence assay | Homo sapiens | 68 | cell-based format | Scientific Literature | ||
| 3. | ALA4384518 | B | Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A23187 stimulation and measured after 1 hr by fluorescence assay | Homo sapiens | 68 | cell-based format | Scientific Literature | ||
| 4. | ALA4384519 | B | Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation at 30 uM preincubated for 30 mins followed by A23187 stimulation and measured after 1 hr by fluorescence assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 5. | ALA4384520 | B | Selectivity ratio of IC50 for human AC8 expressed in HEK293 cells to IC50 for human AC1 expressed in HEK293 cells | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
| 6. | ALA4384523 | A | Cytotoxicity against HEK293 cells expressing human AC1 at 30 uM preincubated for 30 mins followed by A23187 stimulation and measured after 1 hr by CellTiter-Glo luminescent cell viability assay relative to control | Homo sapiens | 68 | cell-based format | Scientific Literature |
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