# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA734269 | B | Noncompetitive inhibition against rat mitochondrial thymidine kinase | 2 | ALA1122068 | single protein format | Scientific Literature | ||
2. | ALA878648 | B | Competitive inhibition against rat cytoplasmic Thymidine kinase | 17 | ALA1122068 | single protein format | Scientific Literature | ||
3. | ALA3232063 | A | Cytotoxicity against mouse P815 cells assessed as growth inhibition after 96 hrs | Mus musculus | 17 | ALA3227997 | cell-based format | Scientific Literature | |
4. | ALA3232065 | F | Antiviral activity against HSV1 2931 infected in African green monkey Vero cells assessed as inhibition of virus replication at 1 ug/ml after 24 hrs relative to control | Human alphaherpesvirus 1 | 17 | ALA3227997 | organism-based format | Scientific Literature | |
5. | ALA3232066 | F | Antiviral activity against HSV1 2931 infected in African green monkey Vero cells assessed as inhibition of virus replication at 10 ug/ml after 24 hrs relative to control | Human alphaherpesvirus 1 | 17 | ALA3227997 | organism-based format | Scientific Literature | |
6. | ALA3232067 | F | Antiviral activity against HSV1 2931 infected in African green monkey Vero cells assessed as inhibition of virus replication at 100 ug/ml after 24 hrs relative to control | Human alphaherpesvirus 1 | 17 | ALA3227997 | organism-based format | Scientific Literature | |
7. | ALA3232068 | A | Cytotoxicity against mouse L5178Y cells assessed as growth inhibition after 96 hrs | Mus musculus | 17 | ALA3227997 | cell-based format | Scientific Literature | |
8. | ALA3232069 | F | Antiviral activity against HSV1 2931 infected in African green monkey Vero cells assessed as inhibition of virus replication at 0.01 ug/ml after 24 hrs relative to control | Human alphaherpesvirus 1 | 17 | ALA3227997 | organism-based format | Scientific Literature | |
9. | ALA3232070 | F | Antiviral activity against HSV1 2931 infected in African green monkey Vero cells assessed as inhibition of virus replication at 0.1 ug/ml after 24 hrs relative to control | Human alphaherpesvirus 1 | 17 | ALA3227997 | organism-based format | Scientific Literature | |
10. | ALA3231330 | B | Inhibition of thymidine kinase in BHK21 (C13) cells using [14C]thymidine at 0.19 mM after 10 mins by liquid scintillation spectrometer analysis relative to control in presence of Mg2+ | Mesocricetus auratus | 2 | ALA3227986 | cell-based format | Scientific Literature | |
11. | ALA3231331 | B | Inhibition of human mitochondrial thymidine kinase using [14C]thymidine at 0.19 mM after 10 mins by liquid scintillation spectrometer analysis relative to control in presence of Mg2+ | Homo sapiens | 2 | ALA3227986 | single protein format | Scientific Literature | |
12. | ALA3231664 | B | Inhibition of human cytoplasmic thymidine kinase using [14C]thymidine at 0.19 mM after 10 mins by liquid scintillation spectrometer analysis relative to control in presence of Mg2+ | Homo sapiens | 2 | ALA3227986 | single protein format | Scientific Literature | |
13. | ALA3257286 | P | Retention time of the compound by liquid chromatography | 15 | ALA3244133 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA3253941 | F | Antiviral activity against HSV1 CL101 infected in African green monkey Vero cells assessed as plaque forming unit at 50 uM after 40 hrs relative to control | Human alphaherpesvirus 1 | 2 | ALA3243955 | organism-based format | Scientific Literature | |
15. | ALA3253945 | A | Cytotoxicity against African green monkey Vero cells at 50 uM after 3 days by haemocytometry | Chlorocebus sabaeus | 2 | ALA3243955 | cell-based format | Scientific Literature | |
16. | ALA3253946 | A | Cytotoxicity against African green monkey Vero cells at 800 uM after 3 days by haemocytometry | Chlorocebus sabaeus | 1 | ALA3243955 | cell-based format | Scientific Literature | |
17. | ALA4651403 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 4,309 | ALA4651402 | organism-based format | IMI-CARE SARS-CoV-2 Data |