# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA874040 | B | Inhibitory concentration against mitogen-activated protein kinase p38 alpha | 53 | ALA1134753 | single protein format | Scientific Literature | ||
2. | ALA1785239 | B | Inhibition of p38alpha | 44 | ALA1782054 | single protein format | Scientific Literature | ||
3. | ALA3988182 | F | GSK PKIS2: Screen against O. lienalis microfilariae, single point, at 3.1uM to assess reduction in motility. Compounds were also tested for cytotoxicity against Rhesus Monkey LLCMK2 cells. A score was assigned as follows: Score 3 = Good activity, 100 % motility reduction; Score 2 = Marginal/moderate activity, 50-99% motility reduction; Score 1 = Inactive, <50% motility reduction; Score 0 = Cytotoxic. | Onchocerca lienalis | 486 | ALA3988181 | cell-based format | Published Kinase Inhibitor Set 2 | |
4. | ALA4310082 | B | Inhibition of BRD4 bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropy | Homo sapiens | 7 | ALA4308848 | assay format | Scientific Literature | |
5. | ALA4310083 | B | Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropy | Homo sapiens | 6 | ALA4308848 | assay format | Scientific Literature | |
6. | ALA4310084 | B | Inhibition of human BRDT bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropy | Homo sapiens | 6 | ALA4308848 | assay format | Scientific Literature | |
7. | ALA4310087 | B | Inhibition of human BRDT bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropy | Homo sapiens | 6 | ALA4308848 | assay format | Scientific Literature | |
8. | ALA5044556 | B | Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan method | Homo sapiens | 8 | ALA5042521 | assay format | Scientific Literature | |
9. | ALA5242783 | B | Binding affinity to p38 alpha (unknown origin) assessed as dissociation constant by DiscoverX kinomescan method | Homo sapiens | 2 | ALA5241103 | single protein format | Scientific Literature |