# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA619783 | B | Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortex | 6 | tissue-based format | Scientific Literature | |||
2. | ALA619789 | B | Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide as a radioligand | 8 | cell membrane format | Scientific Literature | |||
3. | ALA620631 | B | Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of radioligand [3H]GR-65630. | 19 | protein complex format | Scientific Literature | |||
4. | ALA620656 | B | Compound was evaluated for the displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor in rat brain membranes | 2 | cell membrane format | Scientific Literature | |||
5. | ALA875085 | B | Binding affinity to 5-hydroxytryptamine 3 receptor entirely in guinea pig ileum | Cavia porcellus | 4 | tissue-based format | Scientific Literature | ||
6. | ALA620590 | B | Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cells | 8 | cell-based format | Scientific Literature | |||
7. | ALA617969 | B | Binding affinity to 5-hydroxytryptamine 3 receptor of neuronal in the afferent rabbit vagus | Oryctolagus cuniculus | 5 | protein complex format | Scientific Literature | ||
8. | ALA617970 | B | Potency at neuronal 5-hydroxytryptamine 3 receptor in the rabbit heart | Oryctolagus cuniculus | 7 | protein complex format | Scientific Literature | ||
9. | ALA617806 | B | Binding affinity was evaluated in vitro by displacement of [3H]zacopride radioligand from 5-hydroxytryptamine 3 receptor | 7 | protein complex format | Scientific Literature | |||
10. | ALA617709 | B | Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligand | 43 | assay format | Scientific Literature | |||
11. | ALA617713 | F | Antagonistic activity against 5-hydroxytryptamine 3 receptor as inhibition of 5-HT-induced bradycardia (von Bezold-jarisch reflex) in anesthetized rat | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
12. | ALA617717 | F | Inhibition of 5-HT evoked reflex bradycardia in rat. | 20 | organism-based format | Scientific Literature | |||
13. | ALA617720 | F | 5-hydroxytryptamine 3 receptor antagonistic activity measured by inhibition of 5-HT-induced bradycardia (iv administration 10 ug/kg dose in urethane-anesthetized rats) | 30 | organism-based format | Scientific Literature | |||
14. | ALA617721 | F | 5-hydroxytryptamine 3 receptor antagonistic activity as inhibition of 5-HT-induced bradycardia after iv administration of 100 ug/kg dose in urethane-anesthetized rats | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
15. | ALA620616 | B | Compound was evaluated for the displacement of [3H]Q-ICS-205-930 from 5-HT3 recognition sites in rat brain membranes | 5 | cell membrane format | Scientific Literature | |||
16. | ALA619415 | B | Binding affinity to 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand in rat cortex | 6 | assay format | Scientific Literature | |||
17. | ALA619645 | B | pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor | Rattus norvegicus | 9 | protein complex format | Scientific Literature | ||
18. | ALA620723 | B | Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex | 41 | assay format | Scientific Literature | |||
19. | ALA620732 | F | Compound was tested for antagonistic activity against 5-hydroxytryptamine 3 receptor on guinea pig colon at a concentration of 0.3 uM | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
20. | ALA618042 | F | Compound was tested for antagonistic activity against 5-hydroxytryptamine 3 receptor on guinea pig colon at a concentration of 3 uM | Cavia porcellus | 1 | tissue-based format | Scientific Literature |