| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA617994 | B | In vitro binding affinity was measured for 5-hydroxytryptamine 3 receptor in the guinea pig ileum. | Cavia porcellus | 8 | tissue-based format | Scientific Literature | ||
| 2. | ALA617832 | B | The compound was tested for binding affinity against 5-hydroxytryptamine 3 receptor in guinea pig ileum. | Cavia porcellus | 6 | tissue-based format | Scientific Literature | ||
| 3. | ALA617800 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 1000 ug/kg dose in urethane-anesthetized rats | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 4. | ALA617801 | F | Inhibition of 5-HT-induced bradycardia by 5-hydroxytryptamine 3+ | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
| 5. | ALA617720 | F | 5-hydroxytryptamine 3 receptor antagonistic activity measured by inhibition of 5-HT-induced bradycardia (iv administration 10 ug/kg dose in urethane-anesthetized rats) | 30 | organism-based format | Scientific Literature | |||
| 6. | ALA617724 | F | 5-hydroxytryptamine 3 receptor antagonistic activity was measured by the inhibition of 5H+ T-induced bradycardia after iv administration of 3 ug/kg dose in urethane-anesthetized rats | 11 | organism-based format | Scientific Literature | |||
| 7. | ALA617732 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after intravenous administration of 0.3 ug/kg dose in urethane-anesthetized rats | 3 | organism-based format | Scientific Literature | |||
| 8. | ALA617733 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after intravenous administration of 1 ug/kg dose in urethane-anesthetized rats | 4 | organism-based format | Scientific Literature | |||
| 9. | ALA872874 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 0.03 mg/kg dose in urethane-anesthetized rats at 0.05 hour | 1 | organism-based format | Scientific Literature | |||
| 10. | ALA617735 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 0.03 mg/kg dose in urethane-anesthetized rats at 1 hour | 1 | organism-based format | Scientific Literature | |||
| 11. | ALA617736 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 0.03 mg/kg dose in urethane-anesthetized rats at 16 hour | 1 | organism-based format | Scientific Literature | |||
| 12. | ALA617737 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 0.03 mg/kg dose in urethane-anesthetized rats at 3 hour | 1 | organism-based format | Scientific Literature | |||
| 13. | ALA617738 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 0.03 mg/kg dose in urethane-anesthetized rats at 6 hour | 1 | organism-based format | Scientific Literature | |||
| 14. | ALA617742 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 10 ug/kg dose in urethane-anesthetized rats | 1 | organism-based format | Scientific Literature | |||
| 15. | ALA617743 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 3 ug/kg dose in urethane-anesthetized rats | 1 | organism-based format | Scientific Literature | |||
| 16. | ALA617744 | F | Compound was tested for the inhibition of 5-HT-induced bradycardia after peroral administration of 30 ug/kg dose in urethane-anesthetized rats | 4 | organism-based format | Scientific Literature | |||
| 17. | ALA620594 | F | Antagonistic activity evaluated by ability to block serotonin induced relaxation (mediated by activation of 5-hydroxytryptamine 4 receptor) in carbamylcholine (10e-6 M) contracted esophagus at a concentration of 10e-5 M. | Rattus norvegicus | 8 | tissue-based format | Scientific Literature | ||
| 18. | ALA875079 | F | Antagonistic activity by ability to block serotonin induced relaxation (mediated by activation of 5-hydroxytryptamine 4 receptor) in carbamylcholine (10e-6 M) contracted esophagus at a concentration of 10e-6 M. | 51 | tissue-based format | Scientific Literature | |||
| 19. | ALA664800 | A | Inhibition of cytochrome P450 3A4 | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 20. | ALA836230 | A | log (1/Km) value for human liver microsome cytochrome P450 3A4 | Homo sapiens | 58 | tissue-based format | Scientific Literature |
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