| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA818349 | B | Binding of compound towards human Vitamin D3 receptor was determined in vitro; No data | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 2. | ALA818350 | B | Effective concentration required for inhibition of Vitamin D3 receptor | 3 | single protein format | Scientific Literature | |||
| 3. | ALA4622267 | B | Binding affinity to H12 region of zebrafish VDR LBD assessed as stabilization of structural elements forming LBP at 10 fold excess compound concentration by HDX-MS analysis | Danio rerio | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4622270 | B | Binding affinity to H3 and H7 region of zebrafish VDR LBD assessed as stabilization of structural elements by measuring increase in protection at 10 fold excess compound concentration in presence of SRC1 NR2 coactivator peptide measured at 1 mins by HDX-MS analysis | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4622271 | B | Binding affinity to H3 region (253 to 267 residues) of zebrafish VDR LBD assessed as stabilization of structural elements by measuring increase in protection at 10 fold excess compound concentration in presence of SRC1 NR2 coactivator peptide measured at 1 mins by HDX-MS analysis | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4622272 | B | Binding affinity to H6 to H7 region (322 to 344 residues) of zebrafish VDR LBD assessed as stabilization of structural elements by measuring increase in protection at 10 fold excess compound concentration in presence of SRC1 NR2 coactivator peptide measured at 1 mins by HDX-MS analysis | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4622273 | B | Binding affinity to H10 to H11 region (416 to 437 residues) of zebrafish VDR LBD assessed as stabilization of structural elements by measuring increase in protection at 10 fold excess compound concentration in presence of SRC1 NR2 coactivator peptide measured at 1 mins by HDX-MS analysis | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4622274 | B | Binding affinity to H1 region of zebrafish VDR LBD assessed as stabilization of structural elements forming LBP at 10 fold excess compound concentration by HDX-MS analysis | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4622275 | B | Binding affinity to H2 region of zebrafish VDR LBD assessed as stabilization of structural elements forming LBP at 10 fold excess compound concentration by HDX-MS analysis | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4622276 | B | Binding affinity to H5 region (290 to 297 residues) of zebrafish VDR LBD assessed as stabilization of structural elements by measuring increase in protection at 10 fold excess compound concentration in presence of SRC1 NR2 coactivator peptide measured at 1 mins by HDX-MS analysis relative to 1,25D3 | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4622277 | B | Binding affinity to H12 region of zebrafish VDR LBD assessed as stabilization of structural elements at 10 fold excess compound concentration in presence of SRC1 NR2 coactivator peptide by HDX-MS analysis | Danio rerio | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4622278 | B | Binding affinity to zebrafish VDR LBD assessed as Kd for fluorescein-labeled SRC1 NR2 peptide binding by micro-scale thermophoresis method | Danio rerio | 2 | single protein format | Scientific Literature | ||
| 13. | ALA4622279 | B | Antagonist activity at human VDR expressed in HEK293 EBNA cells co-expressing CYP24A1 promoter region assessed as reduction in 1,25D3-induced receptor activation at 0.1 to 1000 nM incubated for 18 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4622280 | B | Antagonist activity at human VDR expressed in HEK293 EBNA cells co-expressing CYP24A1 promoter region assessed as reduction in 1,25D3-induced receptor activation at 0.1 to 1000 nM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4622281 | B | Antagonist activity at full-length zebrafish VDR expressed in rat IEC18 cells co-expressing CYP24A1 promoter region assessed as reduction in 1,25D3-induced receptor activation at 0.1 to 1000 nM incubated for 18 hrs by luciferase reporter gene assay | Danio rerio | 1 | cell-based format | Scientific Literature |
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