# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3796922 | Functional | Antiviral activity against Enterovirus 71 infected in human RD cells assessed as cell viability after 3 days by MTS assay | Enterovirus A71 | 31 | ALA3792372 | organism-based format | Scientific Literature | |
2. | ALA3796923 | ADME | Cytotoxicity against human RD cells | Homo sapiens | 31 | ALA3792372 | cell-based format | Scientific Literature | |
3. | ALA3796924 | Toxicity | Selectivity index, ratio of CC50 for human RD cells to EC50 for Enterovirus 71 | 31 | ALA3792372 | cell-based format | Scientific Literature | ||
4. | ALA638342 | ADME | Index of hydrophobicity (k') | 92 | ALA1123294 | assay format | Scientific Literature | ||
5. | ALA639496 | Binding | Binding affinity against A2 adenosine receptor | Canis lupus familiaris | 20 | ALA1123294 | protein format | Scientific Literature | |
6. | ALA639500 | Binding | Association constant against A2 adenosine receptor | Canis lupus familiaris | 15 | ALA1123294 | protein format | Scientific Literature | |
7. | ALA639501 | Binding | Molar potency ratio (MPR) against adenosine A2 receptor of canine coronary artery | Canis lupus familiaris | 85 | ALA1123294 | protein format | Scientific Literature | |
8. | ALA640780 | Binding | Affinity for adenosine A1 receptor at rat cortical receptors using 1 nM [3H]PIA | Rattus norvegicus | 6 | ALA1125345 | single protein format | Scientific Literature | |
9. | ALA637715 | Binding | Binding affinity to adenosine A1 receptor in rat whole brain membranes by [3H]N6-cyclohexyladenosine displacement. | 16 | ALA1123600 | cell membrane format | Scientific Literature | ||
10. | ALA636674 | Binding | Selectivity as ratio of Ki for binding to adenosine A1 and A2 receptors | Rattus norvegicus | 10 | ALA1125345 | protein format | Scientific Literature | |
11. | ALA649870 | Binding | Affinity for adenosine A2 receptor at rat striatal membrane using 5 nM [3H]CGS-21680 | Rattus norvegicus | 7 | ALA1125345 | assay format | Scientific Literature | |
12. | ALA644771 | Binding | Binding affinity to A2 adenosine receptor in rat striatal membranes by [3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide) displacement. | 16 | ALA1123600 | cell membrane format | Scientific Literature | ||
13. | ALA845135 | Binding | Selectivity ratio of compounds 12a and 12b against A1 receptor | Rattus norvegicus | 2 | ALA1125345 | single protein format | Scientific Literature | |
14. | ALA881826 | Binding | Selectivity ratio of compounds 12a and 12b against A2 receptor | Rattus norvegicus | 2 | ALA1125345 | protein format | Scientific Literature | |
15. | ALA740396 | Functional | Effect on Ataxia in mouse following i.p. administration. | Mus musculus | 18 | ALA1123600 | organism-based format | Scientific Literature | |
16. | ALA740397 | Functional | Effect on Motor activity in mouse following i.p. administration. | Mus musculus | 18 | ALA1123600 | organism-based format | Scientific Literature | |
17. | ALA4828918 | Binding | Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HeLa cell membrane ay 10 uM incubated for 30 mins by microplate beta scintillation counting based radioligand inhibition assay relative to control | Homo sapiens | 13 | ALA4828708 | cell membrane format | Scientific Literature | |
18. | ALA4828920 | Binding | Displacement of [3H]NECA from human adenosine A3 receptor expressed in HeLa cell membrane incubated for 180 mins by microplate beta scintillation counting based radioligand inhibition assay | Homo sapiens | 11 | ALA4828708 | cell membrane format | Scientific Literature | |
19. | ALA4828923 | Binding | Displacement [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membrane incubated for 60 mins by microplate beta scintillation counting based radioligand inhibition assay | Homo sapiens | 7 | ALA4828708 | cell membrane format | Scientific Literature | |
20. | ALA4828924 | Functional | Inhibition of ADP-stimulated platelet aggregation in human whole blood assessed as decrease in platelet activation at 50 uM measured upto 15 mins by whole blood aggregometry assay (Rvb = 641.1 to 708.9 AU.min) | Homo sapiens | 5 | ALA4828708 | tissue-based format | Scientific Literature |