# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA839886 | F | Cytotoxic concentration required to inhibit 50% cell growth in A-549 lung carcinoma cell lines | Homo sapiens | 72 | ALA1125188 | cell-based format | Scientific Literature | |
2. | ALA695204 | F | Cytotoxic concentration required to inhibit 50% cell growth in HT-29 colon adenocarcinoma cell lines | Homo sapiens | 72 | ALA1125188 | cell-based format | Scientific Literature | |
3. | ALA715108 | F | Cytotoxic concentration required to inhibit 50% cell growth in MCF-7 breast carcinoma cell lines | Homo sapiens | 72 | ALA1125188 | cell-based format | Scientific Literature | |
4. | ALA708210 | F | Cytotoxic concentration required to inhibit 50% cell growth in MLM melanoma cell lines | Homo sapiens | 72 | ALA1125188 | cell-based format | Scientific Literature | |
5. | ALA805663 | F | Cytotoxic concentration required to inhibit 50% cell growth in SKMEL-5 melanoma cell lines | Homo sapiens | 72 | ALA1125188 | cell-based format | Scientific Literature | |
6. | ALA2346279 | A | Cytotoxicity against human HepG2 cells after 24 hrs by resazurin assay | Homo sapiens | 30 | ALA2331124 | cell-based format | Scientific Literature | |
7. | ALA2346280 | A | Cytotoxicity against HEK293 cells after 24 hrs by resazurin assay | Homo sapiens | 30 | ALA2331124 | cell-based format | Scientific Literature | |
8. | ALA3111026 | F | Antiinvasive activity against human MCF7/6 cells assessed as minimum log concentration required to show activity after 8 days by hematoxylin and eosin staining-based chick heart invasion assay | Homo sapiens | 9 | ALA3108707 | cell-based format | Scientific Literature | |
9. | ALA3111154 | F | Antiinvasive activity against human MCF7/6 cells assessed as decrease in occupying outer fibroblast-like and myoblast cell layers at 1 umol/L after 8 days by hematoxylin and eosin staining assay | Homo sapiens | 4 | ALA3108707 | cell-based format | Scientific Literature | |
10. | ALA3111158 | F | Antiinvasive activity against human MCF7/6 cells assessed as decrease in occupying outer fibroblast-like and myoblast cell layers at 10 umol/L after 8 days by hematoxylin and eosin staining assay | Homo sapiens | 5 | ALA3108707 | cell-based format | Scientific Literature | |
11. | ALA4421217 | B | Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding by measuring FP-bound fraction at 200 uM using FAM-labelled Prox1 -DNA element incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay relative to control | Mus musculus | 30 | ALA4420080 | cell-based format | Patent Bioactivity Data | |
12. | ALA4421218 | B | Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding by measuring FP-bound fraction at 50 uM using FAM-labelled Prox1 -DNA element incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay relative to control | Mus musculus | 30 | ALA4420080 | cell-based format | Patent Bioactivity Data | |
13. | ALA4421219 | A | Cytotoxicity in HEK293 cells assessed as reduction in cell viability incubated for 24 hrs by Alamar blue dye based assay | Homo sapiens | 30 | ALA4420080 | cell-based format | Patent Bioactivity Data | |
14. | ALA4421220 | A | Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by Alamar blue dye based assay | Homo sapiens | 30 | ALA4420080 | cell-based format | Patent Bioactivity Data |