| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2114817 | F | PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) | 17,358 | ALA1201862 | assay format | PubChem BioAssays | ||
| 2. | ALA2354221 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) | 172,532 | ALA1201862 | assay format | PubChem BioAssays | ||
| 3. | ALA2354282 | F | PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) | 9,957 | ALA1201862 | assay format | PubChem BioAssays | ||
| 4. | ALA2354287 | F | PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) | 39,968 | ALA1201862 | assay format | PubChem BioAssays | ||
| 5. | ALA4029928 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated NO production at 20 uM by ELISA relative to control | Mus musculus | 25 | ALA4028822 | cell-based format | Scientific Literature | |
| 6. | ALA4029931 | A | Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as cell viability at 20 uM by MTT assay (Rvb = 100.01 +/- 0.05 %) | Mus musculus | 25 | ALA4028822 | cell-based format | Scientific Literature | |
| 7. | ALA5115423 | A | Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation at 10 uM in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control | Homo sapiens | 31 | ALA5113402 | microsome format | Scientific Literature | |
| 8. | ALA5115424 | A | Inhibition of CYP450 in human liver microsomes assessed as inhibition of EpETrE formation at 10 uM in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control | Homo sapiens | 31 | ALA5113402 | microsome format | Scientific Literature | |
| 9. | ALA5115425 | B | Selectivity index, log ratio of Inhibition of CYP450 in human liver microsomes assessed as inhibition of EpETrE formation in presence of arachidonic acid to Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid | Homo sapiens | 31 | ALA5113402 | assay format | Scientific Literature | |
| 10. | ALA5115426 | A | Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis | Homo sapiens | 1 | ALA5113402 | microsome format | Scientific Literature | |
| 11. | ALA5115427 | A | Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA5113402 | microsome format | Scientific Literature | |
| 12. | ALA5115428 | A | Inhibition of CYP450 in Sprague-Dawley rat liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA5113402 | microsome format | Scientific Literature | |
| 13. | ALA5115429 | A | Inhibition of CYP450 in Sprague-Dawley rat liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5113402 | microsome format | Scientific Literature | |
| 14. | ALA5115430 | A | Inhibition of CYP450 in B6C3F1 mouse liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control | Mus musculus | 1 | ALA5113402 | microsome format | Scientific Literature | |
| 15. | ALA5115431 | A | Inhibition of CYP450 in B6C3F1 mouse liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis | Mus musculus | 1 | ALA5113402 | microsome format | Scientific Literature | |
| 16. | ALA5115432 | A | Inhibition of recombinant human CYP4F2 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 mins by jump-dilution assay relative to control | Homo sapiens | 1 | ALA5113402 | cell-based format | Scientific Literature | |
| 17. | ALA5115433 | A | Inhibition of recombinant human CYP4F2 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 mins by jump-dilution assay | Homo sapiens | 1 | ALA5113402 | cell-based format | Scientific Literature | |
| 18. | ALA5115434 | A | Inhibition of recombinant human CYP4A11 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 mins by jump-dilution assay relative to control | Homo sapiens | 1 | ALA5113402 | cell-based format | Scientific Literature | |
| 19. | ALA5115435 | A | Inhibition of recombinant human CYP4A11 expressed in baculovirus-infected insect cells at 50 uM incubated for 15 mins in presence of arachidonic acid and NADPH by jump-dilution assay relative to control | Homo sapiens | 1 | ALA5113402 | cell-based format | Scientific Literature | |
| 20. | ALA5115436 | A | Inhibition of recombinant human CYP2J2 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 mins by jump-dilution assay relative to control | Homo sapiens | 1 | ALA5113402 | cell-based format | Scientific Literature |
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