# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA800778 | F | Inhibition of SP-induced salvation after intraperitoneal administration of the durg at a concentration of 50 mg/kg in rats | Rattus norvegicus | 13 | organism-based format | Scientific Literature | ||
2. | ALA812239 | B | Binding affinity towards Tachykinin receptor 1 binding in guinea pig cerebral cortex membranes was determined using [3H]SP as the radioligand | Cavia porcellus | 16 | tissue-based format | Scientific Literature | ||
3. | ALA807965 | B | Binding affinity towards Tachykinin receptor 1 in human IM-9 cells using [3H]-substance P as ligand | 16 | cell-based format | Scientific Literature | |||
4. | ALA813323 | B | Binding affinity towards Tachykinin receptor 1 in rat cerebral cortex membranes was determined by using 125 [I]-BHSP as radioligand | 15 | cell membrane format | Scientific Literature | |||
5. | ALA813646 | B | Ability to displace the binding of [125I]iodohistidyl-NKA to Tachykinin receptor 2 in hamster urinary bladder membranes was determined. | Cricetulus griseus | 13 | cell membrane format | Scientific Literature | ||
6. | ALA815573 | B | Ability to displace the binding of [3H]-Senktide to Tachykinin receptor 3 in rat cerebral cortex membranes was determined. | 13 | cell membrane format | Scientific Literature | |||
7. | ALA841890 | F | Inhibition of SP-induced plasma extravasation in guinea pig after peroral administration at a dose 15 mg/kg | Cavia porcellus | 14 | organism-based format | Scientific Literature | ||
8. | ALA841891 | F | Inhibition of capsaicin-induced plasma extravasation after 10 mL injection of 30 uM capsaicin in to the peritoneal cavity of guinea pig ureter | Cavia porcellus | 10 | organism-based format | Scientific Literature | ||
9. | ALA846494 | B | Ratio of binding affinity for NK1 receptor in guinea pig to that of rat was determined | 14 | single protein format | Scientific Literature | |||
10. | ALA882909 | B | Inhibitory concentration against tachykinin receptor 1 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
11. | ALA882910 | B | Inhibitory concentration against tachykinin receptor 2 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
12. | ALA4192665 | F | Antagonist activity at His6-tagged NK1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of substance-P-induced IP1 accumulation preincubated for 10 mins followed by substance-P addition measured after 30 mins by HTRF-FRET assay | Homo sapiens | 4 | cell-based format | Scientific Literature |