| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA890257 | B | Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay | Homo sapiens | 13 | ALA1145453 | cell-based format | Scientific Literature | |
| 2. | ALA890258 | B | Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay | Homo sapiens | 13 | ALA1145453 | cell-based format | Scientific Literature | |
| 3. | ALA890259 | F | Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay | Homo sapiens | 13 | ALA1145453 | cell-based format | Scientific Literature | |
| 4. | ALA890261 | F | Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay | Homo sapiens | 13 | ALA1145453 | cell-based format | Scientific Literature | |
| 5. | ALA2149726 | B | Inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 30 mins by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
| 6. | ALA2149727 | B | Inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3) using Dabcyl-KNSTLQSGLRKE-Edan as substrate after 60 mins by FRET analysis | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
| 7. | ALA2149728 | B | Time dependent inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate at 3 to 100 uM up to 120 mins | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
| 8. | ALA2149730 | B | Inhibition of SARS-CoV PLpro deubiququitination expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate at 200 uM by fluorescence analysis | SARS coronavirus | 2 | ALA2146458 | assay format | Scientific Literature | |
| 9. | ALA2149731 | B | Inhibition of chymotrypsin using N-benzoyl-L-tyrosine ethyl ester as substrate assessed as benzoyl-tyrosine production measured every 10 seconds for 6 mins | 5 | ALA2146458 | assay format | Scientific Literature | ||
| 10. | ALA2149733 | B | Inhibition of papaya papain using N-alpha-benzoyl-L-arginine-pnitroanilide as substrate at 200 uM after 5 mins | Carica papaya | 4 | ALA2146458 | single protein format | Scientific Literature | |
| 11. | ALA2149735 | B | Inhibition of Human immunodeficiency virus 1 protease preincubated for 10 mins by FRET assay | Human immunodeficiency virus 1 | 6 | ALA2146458 | single protein format | Scientific Literature | |
| 12. | ALA2150310 | B | Time dependent inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3) using Dabcyl-KNSTLQSGLRKE-Edan as substrate at 1 to 100 uM by FRET analysis | SARS coronavirus | 6 | ALA2146458 | assay format | Scientific Literature | |
| 13. | ALA2150311 | B | Time dependent inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate at IC50 by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
| 14. | ALA2150312 | B | Inhibition of SARS-CoV PLpro expressed in Escherichia coli (DE3) BL21 using Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 60 mins by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
| 15. | ALA2150313 | B | Inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate by fluorescence assay | SARS coronavirus | 7 | ALA2146458 | assay format | Scientific Literature | |
| 16. | ALA2150315 | B | Non competitive inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3) using Dabcyl-KNSTLQSGLRKE-Edan as substrate by Dixon plot analysis | SARS coronavirus | 6 | ALA2146458 | assay format | Scientific Literature | |
| 17. | ALA2150316 | B | Non competitive inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate by Dixon plot analysis | SARS coronavirus | 6 | ALA2146458 | assay format | Scientific Literature | |
| 18. | ALA3294386 | B | Inhibition of EZH2 histone methyltransferase activity in EZH2/SUZ12/EED protein complex (unknown origin) using histone H3 peptide/S-adenosylmethionine as substrate after 2 hrs by TR-FRET assay | Homo sapiens | 7 | ALA3286358 | protein complex format | Scientific Literature |
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