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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2149508 F Partial agonist activity at RXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 2. ALA2149509 F Partial agonist activity at RXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay relative to 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 3. ALA2149510 F Partial agonist activity at RXRbeta expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 4. ALA2149511 F Partial agonist activity at RXRgamma expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 5. ALA2149512 F Partial antagonist activity at RXRalpha expressed in human Cos1 cells assessed as reduction in LGD1069-induced luciferase activity after 18 hrs by SEAP reporter gene assay Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 6. ALA2149513 B Transactivation of RARalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 7. ALA2149514 B Transactivation of RARbeta expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 8. ALA2149515 B Transactivation of RARgamma expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 1 ALA2146420 cell-based format Scientific Literature 9. ALA2149516 F Agonist activity at PPARgamma expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 3 ALA2146420 cell-based format Scientific Literature 10. ALA2149517 F Agonist activity at PPARgamma/RXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 3 ALA2146420 cell-based format Scientific Literature 11. ALA2149518 F Agonist activity at LXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 3 ALA2146420 cell-based format Scientific Literature 12. ALA2149519 F Agonist activity at LXRalpha/RXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay Homo sapiens 3 ALA2146420 cell-based format Scientific Literature 13. ALA2149520 A Drug level in ICR mouse serum at 30 mg/kg, po Mus musculus 3 ALA2146420 organism-based format Scientific Literature 14. ALA2149521 T Toxicity in ICR mouse assessed as increase in body weight at 30 mg/kg/day, po for 7 days relative to vehicle-treated control Mus musculus 3 ALA2146420 organism-based format Scientific Literature 15. ALA2149522 T Toxicity in ICR mouse assessed as increase in liver weight at 30 mg/kg/day, po for 7 days relative to vehicle-treated control Mus musculus 3 ALA2146420 organism-based format Scientific Literature 16. ALA2149950 T Toxicity in ICR mouse assessed as increase in serum triglyceride level at 30 mg/kg/day, po for 7 days relative to vehicle-treated control Mus musculus 2 ALA2146420 organism-based format Scientific Literature 17. ALA2149951 T Toxicity in male Sprague-Dawley rat assessed as change in body weight at 30 mg/kg/day, po for 28 days relative to vehicle-treated control Rattus norvegicus 1 ALA2146420 organism-based format Scientific Literature 18. ALA2149952 T Toxicity in female Sprague-Dawley rat assessed as change in body weight at 30 mg/kg/day, po for 28 days relative to vehicle-treated control Rattus norvegicus 1 ALA2146420 organism-based format Scientific Literature 19. ALA2149953 T Toxicity in male Sprague-Dawley rat assessed as change in water intake at 30 mg/kg/day, po for 28 days relative to vehicle-treated control Rattus norvegicus 1 ALA2146420 organism-based format Scientific Literature 20. ALA2149954 T Toxicity in female Sprague-Dawley rat assessed as change in water intake at 30 mg/kg/day, po for 28 days relative to vehicle-treated control Rattus norvegicus 1 ALA2146420 organism-based format Scientific Literature