# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2150722 | F | Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substrate addition by FRET assay | Pseudomonas aeruginosa | 13 | assay format | Scientific Literature | ||
2. | ALA2150723 | F | Antagonist activity at Pseudomonas aeruginosa PA14 LasB assessed as inhibition of swarming at 25 uM after 16 hrs swarming motility assay relative to control | Pseudomonas aeruginosa PA14 | 4 | assay format | Scientific Literature | ||
3. | ALA2150724 | A | Toxicity against Pseudomonas aeruginosa PA14 assessed as viability at 25 uM by spectrophotometry | Pseudomonas aeruginosa | 2 | organism-based format | Scientific Literature | ||
4. | ALA2150725 | P | Metabolic stability in tryptic soy broth assessed as S-oxidation at 50 uM after 48 hrs | 4 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA2150726 | P | Metabolic stability in tryptic soy broth assessed as decomposition at 50 uM after 48 hrs | 4 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4673773 | B | Zinc chelating activity mediated inhibition of Clostridium botulinum Hall A hyper BoNT/A1activity assessed as inhibition of BoNT/A1-induced neurotoxicity in hIPSC derived GABA neurons by measuring protection against SNAP-25 cleavage incubated for 30 mins post BoNT/A1 addition and measured at 7 hrs post-toxin addition by Western blot analysis | Clostridium botulinum | 7 | assay format | Scientific Literature | ||
7. | ALA4673782 | B | Zinc chelating activity mediated inhibition of Clostridium botulinum BoNT/A1 LC (1 to 425 residues) activity using SNAPtide as substrate incubated with enzyme for 30 mins followed by substrate addition and measured for 20 mins by FRET assay relative to control | Clostridium botulinum | 19 | assay format | Scientific Literature |