# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2150722 | Functional | Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substrate addition by FRET assay | Pseudomonas aeruginosa | 13 | ALA2146446 | assay format | Scientific Literature | |
2. | ALA2150723 | Functional | Antagonist activity at Pseudomonas aeruginosa PA14 LasB assessed as inhibition of swarming at 25 uM after 16 hrs swarming motility assay relative to control | Pseudomonas aeruginosa PA14 | 4 | ALA2146446 | assay format | Scientific Literature | |
3. | ALA2150724 | ADME | Toxicity against Pseudomonas aeruginosa PA14 assessed as viability at 25 uM by spectrophotometry | Pseudomonas aeruginosa | 2 | ALA2146446 | organism-based format | Scientific Literature | |
4. | ALA2150725 | Physicochemical | Metabolic stability in tryptic soy broth assessed as S-oxidation at 50 uM after 48 hrs | 4 | ALA2146446 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA2150726 | Physicochemical | Metabolic stability in tryptic soy broth assessed as decomposition at 50 uM after 48 hrs | 4 | ALA2146446 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA5243566 | Binding | Inhibition of MMP-2 (unknown origin) | Homo sapiens | 1 | ALA5241119 | single protein format | Scientific Literature | |
7. | ALA5243567 | Binding | Inhibition of MMP-3 (unknown origin) | Homo sapiens | 1 | ALA5241119 | single protein format | Scientific Literature | |
8. | ALA5243568 | Binding | Inhibition of MMP-9 (unknown origin) | Homo sapiens | 1 | ALA5241119 | single protein format | Scientific Literature | |
9. | ALA5243569 | Binding | Inhibition of anthrax lethal factor | Bacillus anthracis | 2 | ALA5241119 | single protein format | Scientific Literature | |
10. | ALA5257279 | Binding | Inhibition of Pseudomonas aeruginosa LasB elastase using aminobenzoyl-Ala-Gly-Leu-Ala-p-nitro-benzyl-amide as substrate b microtiter-based fluorimetric assay | Pseudomonas aeruginosa | 5 | ALA5257018 | single protein format | Scientific Literature |