| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2150655 | B | Activation of KCNQ2/Q3 | 3 | protein complex format | Scientific Literature | |||
| 2. | ALA4354740 | B | Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA4354741 | B | Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay relative to retigabine | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 4. | ALA4354742 | A | Plasma clearance in rat at 1 mg/kg. iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4354743 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4354744 | A | Oral bioavailability in rat at 1 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4354745 | A | AUC in rat at 1 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4354746 | A | Ratio of drug level in brain to plasma in rat | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
| 9. | ALA4354747 | F | Antiallodynic activity in rat model of capsaicin-induced mechanical hyperalgesia assessed as increase in paw withdrawal threshold at 3 mg/kg, ip administered 30 mins before capsaicin addition relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4354748 | F | Antiallodynic activity in rat model of capsaicin-induced mechanical hyperalgesia assessed as increase in paw withdrawal threshold at 10 mg/kg, ip administered 30 mins before capsaicin addition relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4354749 | F | Antiallodynic activity in rat model of capsaicin-induced mechanical hyperalgesia assessed as increase in paw withdrawal threshold at 30 mg/kg, ip administered 30 mins before capsaicin addition relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4354750 | F | Antiallodynic activity in ip dosed rat model of capsaicin-induced mechanical hyperalgesia assessed as increase in paw withdrawal threshold administered 30 mins before capsaicin addition | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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