# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2148814 | F | Antiobesity activity in high fat diet-induced obese Sprague-Dawley rat assessed as reduction of food intake at 10 mg/kg, po administered daily for 3 days relative to dirlotapide | Rattus norvegicus | 8 | ALA2146366 | organism-based format | Scientific Literature | |
2. | ALA2148815 | F | Antiobesity activity in high fat diet-induced obese Sprague-Dawley rat assessed as reduction in body weight at 10 mg/kg, po administered daily for 3 days relative to dirlotapide | Rattus norvegicus | 8 | ALA2146366 | organism-based format | Scientific Literature | |
3. | ALA2148816 | F | Antiobesity activity in high fat diet-induced obese Sprague-Dawley rat assessed as reduction of triglyceride accumulation in liver at 10 mg/kg, po administered daily for 3 days relative to dirlotapide | Rattus norvegicus | 8 | ALA2146366 | organism-based format | Scientific Literature | |
4. | ALA2150034 | F | Antiobesity activity in high fat diet-induced obese Sprague-Dawley rat assessed as reduction of triglyceride accumulation in liver at 10 mg/kg, po administered daily for 3 days relative to control | Rattus norvegicus | 9 | ALA2146366 | organism-based format | Scientific Literature | |
5. | ALA2150035 | F | Antiobesity activity in high fat diet-induced obese Sprague-Dawley rat assessed as reduction in body weight at 10 mg/kg, po administered daily for 3 days relative to control | Rattus norvegicus | 9 | ALA2146366 | organism-based format | Scientific Literature | |
6. | ALA2150036 | F | Antiobesity activity in high fat diet-induced obese Sprague-Dawley rat assessed as reduction of food intake at 10 mg/kg, po administered daily for 3 days relative to control | Rattus norvegicus | 9 | ALA2146366 | organism-based format | Scientific Literature | |
7. | ALA2150037 | A | Fraction unbound in human HepG2 cells by equilibrium dialysis | Homo sapiens | 19 | ALA2146366 | cell-based format | Scientific Literature | |
8. | ALA2150038 | B | Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISA | Homo sapiens | 19 | ALA2146366 | cell-based format | Scientific Literature | |
9. | ALA2150039 | B | Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISA | Homo sapiens | 25 | ALA2146366 | cell-based format | Scientific Literature |