| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2156213 | B | Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation counting | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA2156214 | B | Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation counting | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA2156215 | B | Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cell membrane by liquid scintillation counting | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA2156216 | B | Selectivity index, ratio of Ki for human DOR to Ki for human MOR by radioligand displacement assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA2156217 | B | Displacement of [3H]naloxone from MOR in rat brain homogenates by liquid scintillation counting | Rattus norvegicus | 5 | tissue-based format | Scientific Literature | ||
| 6. | ALA2156218 | B | Displacement of [3H]deltorphin2 from DOR in rat brain homogenates by liquid scintillation counting | Rattus norvegicus | 5 | tissue-based format | Scientific Literature | ||
| 7. | ALA2156219 | F | Agonist activity at human MOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillation counting | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA2156323 | F | Agonist activity at human MOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillation counting relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA2156324 | F | Agonist activity at human DOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillation counting | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA2156325 | F | Agonist activity at human DOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillation counting relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA2156326 | B | Selectivity index, ratio of EC50 for rat brain DOR to EC50 for rat brain MOR by cAMP accumulation assay | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
| 12. | ALA2156327 | F | Agonist activity at human MOR expressed in HEK293 cells assessed as stimulation of ERK1/2 phosphorylation at 1 uM after 2 mins by Western blotting | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA2156329 | F | Agonist activity at human DOR expressed in HEK293 cells assessed as stimulation of ERK1/2 phosphorylation at 1 uM after 2 mins by Western blotting | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA2156330 | F | Agonist activity at MOR/DOR in in NMRI mouse spinal cord assessed as reduction in spinal cord network activity by electrophysiology assay | Mus musculus | 4 | assay format | Scientific Literature | ||
| 15. | ALA2156331 | F | Agonist activity at MOR/DOR in in NMRI mouse frontal cortex assessed as reduction in spinal cord network activity by electrophysiology assay | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
| 16. | ALA2156766 | F | Agonist activity at MOR/DOR in in NMRI mouse frontal cortex or spinal cord networks assessed as reduction in spinal cord network activity by electrophysiology assay relative to sufentanil | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
| 17. | ALA2156767 | F | Agonist activity at MOR/DOR in in NMRI mouse frontal cortex or spinal cord networks assessed as reduction in spinal cord network activity by electrophysiology assay relative to gabapentin | Mus musculus | 4 | tissue-based format | Scientific Literature |
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