| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2155377 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase reporter assay | Mus musculus | 28 | cell-based format | Scientific Literature | ||
| 2. | ALA2155378 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase reporter assay relative to cyclopamine | Mus musculus | 23 | cell-based format | Scientific Literature | ||
| 3. | ALA2155381 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity after 48 hrs by RT-PCR analysis in presence of SAG | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA2155382 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activity | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA2155383 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by BetaGLo assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA2155384 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by BetaGLo assay in presence of SAG | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA2153868 | B | Allosteric inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of SAG-induced Gli1 transcriptional activity at 103 to 25000 nM by qPCr analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA2153872 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activity in presence of SAG | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA2153873 | B | Ratio of IC50 for Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity in presence of SAG to IC50 for Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA2153875 | B | Competitive inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of purmorphamine-induced Gli1 transcriptional activity at 309 to 25000 nM by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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