# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2155377 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase reporter assay | Mus musculus | 28 | cell-based format | Scientific Literature | ||
2. | ALA2155378 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase reporter assay relative to cyclopamine | Mus musculus | 23 | cell-based format | Scientific Literature | ||
3. | ALA2155379 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity after 48 hrs by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
4. | ALA2155380 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity after 48 hrs by RT-PCR analysis relative to cyclopamine | Mus musculus | 2 | cell-based format | Scientific Literature | ||
5. | ALA2155381 | B | Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity after 48 hrs by RT-PCR analysis in presence of SAG | Mus musculus | 3 | cell-based format | Scientific Literature | ||
6. | ALA2155382 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activity | Mus musculus | 3 | cell-based format | Scientific Literature | ||
7. | ALA2155383 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by BetaGLo assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
8. | ALA2155384 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by BetaGLo assay in presence of SAG | Mus musculus | 3 | cell-based format | Scientific Literature | ||
9. | ALA2153868 | B | Allosteric inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of SAG-induced Gli1 transcriptional activity at 103 to 25000 nM by qPCr analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
10. | ALA2153871 | B | Competitive inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of purmorphamine-induced Gli1 transcriptional activity at 103 to 25000 nM by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA2153872 | B | Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activity in presence of SAG | Mus musculus | 3 | cell-based format | Scientific Literature | ||
12. | ALA2153873 | B | Ratio of IC50 for Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity in presence of SAG to IC50 for Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity | Mus musculus | 2 | cell-based format | Scientific Literature |