| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2156127 | F | Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level by FLIPR assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 2. | ALA2155421 | A | Intrinsic clearance in rat liver microsomes preincubated for 5 mins before addition of NADPH measured after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 51 | microsome format | Scientific Literature | ||
| 3. | ALA2155423 | F | Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level by FLIPR assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA2155424 | F | Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA2155425 | A | Cmax in Wistar rat at 5 mg/kg, iv by LC/MS/MS analysis | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA2155426 | A | Plasma clearance in Wistar rat at 5 mg/kg, iv | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 7. | ALA2155427 | A | Volume of distribution at steady state in Wistar rat at 5 mg/kg, iv | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 8. | ALA2155428 | A | Terminal half life in Wistar rat at 5 mg/kg, iv | Rattus norvegicus | 7 | organism-based format | Scientific Literature |
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