# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2155338 | Binding | Displacement of [3H]prazosin from human cloned alpha1B adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counter | Homo sapiens | 12 | ALA2150980 | cell-based format | Scientific Literature | |
2. | ALA2155339 | Binding | Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counter | Homo sapiens | 12 | ALA2150980 | cell-based format | Scientific Literature | |
3. | ALA2155340 | Binding | Ratio of pA2 for alpha1A adrenoceptor to pA2 for alpha1B adrenoceptor in Sprague-Dawley rat | Rattus norvegicus | 6 | ALA2150980 | assay format | Scientific Literature | |
4. | ALA2155385 | Binding | Displacement of [3H]prazosin from human cloned alpha1D adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counter | Homo sapiens | 12 | ALA2150980 | cell-based format | Scientific Literature | |
5. | ALA2155386 | Binding | Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranes after 30 mins by liquid scintillation counting | Rattus norvegicus | 12 | ALA2150980 | cell membrane format | Scientific Literature | |
6. | ALA2155387 | Functional | Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostate assessed as inhibition of noradrenaline-induced contractions after 30 mins | Rattus norvegicus | 6 | ALA2150980 | tissue-based format | Scientific Literature | |
7. | ALA2155388 | Functional | Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as inhibition of noradrenaline-induced contractions after 30 mins | Rattus norvegicus | 6 | ALA2150980 | tissue-based format | Scientific Literature | |
8. | ALA2155389 | Functional | Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins | Rattus norvegicus | 6 | ALA2150980 | tissue-based format | Scientific Literature | |
9. | ALA2155390 | Functional | Antagonist activity at alpha1D adrenoceptor in Sprague-Dawley rat thoracic aorta assessed as inhibition of noradrenaline-induced contractions after 30 mins | Rattus norvegicus | 6 | ALA2150980 | tissue-based format | Scientific Literature | |
10. | ALA2155391 | Functional | Antagonist activity at alpha2 adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as suppression of clonidine-mediated inhibition of twitch response after 30 mins | Rattus norvegicus | 6 | ALA2150980 | tissue-based format | Scientific Literature | |
11. | ALA2155392 | Binding | Ratio of pA2 for alpha1D adrenoceptor to pA2 for alpha1B adrenoceptor in Sprague-Dawley rat | Rattus norvegicus | 6 | ALA2150980 | assay format | Scientific Literature | |
12. | ALA2155393 | Binding | Ratio of pA2 for alpha1A adrenoceptor to pA2 for alpha1D adrenoceptor in Sprague-Dawley rat | Rattus norvegicus | 6 | ALA2150980 | assay format | Scientific Literature | |
13. | ALA2155394 | Functional | Inverse agonist activity at alpha1A adrenoceptor in guinea pig thoracic aorta assessed as inhibition of ca2+-induced IRT at 10 nM after 30 mins | Cavia porcellus | 6 | ALA2150980 | tissue-based format | Scientific Literature |