# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2154125 | Binding | Inhibition of SCD-1 activity in Sprague-Dawley rat microsome assessed as reduction in [I-14C] stearoyl CoA desaturation by scintillation counting | Rattus norvegicus | 5 | ALA2150952 | microsome format | Scientific Literature | |
2. | ALA2154126 | Binding | Inhibition of SCD-1 activity in organic anion transporting polypeptides-deficient human HepG2 cells assessed as reduction in [I-14C] stearoyl CoA desaturation by scintillation counting | Homo sapiens | 5 | ALA2150952 | cell-based format | Scientific Literature | |
3. | ALA2154127 | Binding | Inhibition of SCD-1 activity in Sprague-Dawley rat Hepatocytes expressing organic anion transporting polypeptides assessed as reduction in [I-14C] stearoyl CoA desaturation by scintillation counting | Rattus norvegicus | 5 | ALA2150952 | cell-based format | Scientific Literature | |
4. | ALA2154128 | Binding | Ratio IC50 for SCD-1 activity in organic anion transporting polypeptides-deficient human HepG2 cells to IC50 for SCD-1 activity in Sprague-Dawley rat Hepatocytes expressing organic anion transporting polypeptides | 5 | ALA2150952 | cell-based format | Scientific Literature | ||
5. | ALA2154132 | Binding | Inhibition of rat delta-5 desaturase activity expressed in human HEpG2 cells | Rattus norvegicus | 5 | ALA2150952 | cell-based format | Scientific Literature | |
6. | ALA2154133 | Binding | Inhibition of human delta-5 desaturase activity expressed in human HEpG2 cells | Homo sapiens | 5 | ALA2150952 | cell-based format | Scientific Literature | |
7. | ALA2154134 | Binding | Inhibition of rat delta-6 desaturase activity expressed in human HEpG2 cells | Rattus norvegicus | 5 | ALA2150952 | cell-based format | Scientific Literature | |
8. | ALA2154135 | Binding | Inhibition of human delta6 desaturase activity expressed in human HEpG2 cells | Homo sapiens | 5 | ALA2150952 | cell-based format | Scientific Literature | |
9. | ALA2154156 | ADME | Ratio drug uptake in liver to harderian gland of C57BL6 mouse at 10 mg/kg, po measured 6 hrs post dose | Mus musculus | 5 | ALA2150952 | organism-based format | Scientific Literature |