# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2160758 | A | Photostability of the compound in 17% bovine calf serum assessed as rate of photobleaching at 6.5 uM after 20 to 22 mins in presence of light (75 mW/cm'2) | 3 | assay format | Scientific Literature | |||
2. | ALA2160760 | A | Drug uptake in human BCC1 cells assessed as deposition in mitochondria at 200 nM after 30 mins by phase contrast microscopy | Homo sapiens | 4 | mitochondrion format | Scientific Literature | ||
3. | ALA2160761 | A | Drug uptake in human BCC1 cells assessed as deposition in mitochondria at 200 nM after 30 mins by HPPH fluorescence spectrophotometry | Homo sapiens | 4 | mitochondrion format | Scientific Literature | ||
4. | ALA2160762 | A | Drug uptake in human BCC1 cells at 200 nM incubated for 30 mins measured after 4 to 24 hrs by fluorescent microscopy | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA2160763 | A | Ratio of drug uptake in human BCC1 cells in serum free medium to drug uptake in human BCC1 cells in medium containing 10% fetal calf serum by fluorescent microscopy | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA2162210 | F | Reduction in STAT3 cross linking level in human BCC1 cells assessed as dimerization of STAT3 after 9 mins by Western blotting in presence of 665 nm light | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA2162211 | F | Reduction in EGFR levels in human BCC1 cells after 9 mins by Western blotting in presence of 665 nm laser light | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA2162212 | B | Activation of p38 MAPK in human BCC1 cells assessed as dimerization of STAT3 after 9 mins by Western blotting in presence of 665 nm laser light | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA2162213 | F | Induction of apoptosis in human BCC1 cells assessed as survival after 24 hrs by trypan blue assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA2162223 | F | Photosensitizing activity in mouse Colon 26 assessed as cell viability at 0.0625 uM after 24 hrs followed by illumination with 665 nm laser light and 48 hrs incubation in dark by MTT assay in presence of serum | Mus musculus | 3 | cell-based format | Scientific Literature | ||
11. | ALA2162224 | A | Drug uptake in mouse Colon 26 cells at 400 nM after 24 hrs by flow cytometry | Mus musculus | 3 | cell-based format | Scientific Literature | ||
12. | ALA2162225 | A | Drug uptake in mouse Colon 26 cells at 800 nM after 24 hrs by flow cytometry | Mus musculus | 3 | cell-based format | Scientific Literature | ||
13. | ALA2162226 | F | Antitumor activity against mouse Colon 26 cells xenografted in parenterally dosed BALB/c mouse assessed as tumor cure at 1 umol/kg after 24 hrs followed by illumination with 128 J/cm'2, 14 mW/cm'2 laser light measured after 60 days | Mus musculus | 4 | organism-based format | Scientific Literature | ||
14. | ALA2163141 | A | Drug uptake in BALB/c mouse xenografted with mouse Colon 26 cells at 1 umol/kg, iv after 24 hrs by fluorescence imaging | Mus musculus | 3 | organism-based format | Scientific Literature | ||
15. | ALA2163142 | A | Drug uptake in BALB/c mouse xenografted with mouse Colon 26 cells at 1 umol/kg, iv after 48 hrs by fluorescence imaging | Mus musculus | 3 | organism-based format | Scientific Literature | ||
16. | ALA2163143 | A | Drug uptake in BALB/c mouse xenografted with mouse Colon 26 cells at 1 umol/kg, iv after 72 hrs by fluorescence imaging | Mus musculus | 3 | organism-based format | Scientific Literature | ||
17. | ALA2163144 | A | Drug uptake in BALB/c mouse tumor xenografted with mouse Colon 26 cells at 1 umol/kg, iv after 24 hrs by fluorescence imaging | Mus musculus | 3 | organism-based format | Scientific Literature | ||
18. | ALA2163145 | A | Drug uptake in skin of BALB/c mouse xenografted with mouse Colon 26 cells measured after removal of tumor at 1 umol/kg, iv after 24 hrs by fluorescence imaging | Mus musculus | 2 | organism-based format | Scientific Literature | ||
19. | ALA2163146 | A | Drug uptake in tumor of BALB/c mouse xenografted with mouse Colon 26 cells at 1 umol/kg, iv after 24 hrs by fluorescence imaging | Mus musculus | 2 | organism-based format | Scientific Literature |