# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2161942 | Binding | Inhibition of GST-tagged human ALK cytoplasmic domain (1058-1620) expressed in Sf21 insect cells using GST-tagged human recombinant PLC-gamma/substrate by ELISA | Homo sapiens | 25 | ALA2157957 | cell-based format | Scientific Literature | |
2. | ALA2161943 | ADME | Half life in Sprague-Dawley rat liver microsomes at 0.5 uM preincubated for 10 mins before NADPH and UDPGA challenge | Rattus norvegicus | 13 | ALA2157957 | microsome format | Scientific Literature | |
3. | ALA2161944 | ADME | Half life in monkey liver microsomes at 0.5 uM preincubated for 10 mins before NADPH and UDPGA challenge | Macaca mulatta | 10 | ALA2157957 | microsome format | Scientific Literature | |
4. | ALA2161945 | ADME | Half life in human liver microsomes at 0.5 uM preincubated for 10 mins before NADPH and UDPGA challenge | Homo sapiens | 10 | ALA2157957 | microsome format | Scientific Literature | |
5. | ALA2162287 | Binding | Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assay | Homo sapiens | 19 | ALA2157957 | cell-based format | Scientific Literature | |
6. | ALA2162288 | ADME | Half life in CD1 mouse liver microsomes at 0.5 uM preincubated for 10 mins before NADPH and UDPGA challenge | Mus musculus | 9 | ALA2157957 | microsome format | Scientific Literature |