# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2162319 | B | Inhibition of fluorescently labeled VER51001 binding to full length human HSP90beta after 30 mins by fluorescence polarization assay | Homo sapiens | 47 | single protein format | Scientific Literature | ||
2. | ALA2162322 | B | Displacement of [3H]-dofetilide from human ERG | Homo sapiens | 7 | single protein format | Scientific Literature | ||
3. | ALA2162323 | B | Inhibition of human ERG expressed in HEK293 cells by voltage-clamp method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA2162324 | F | Antiproliferative activity against human BT474 cells after 4 days by SRB method | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
5. | ALA2162325 | F | Antiproliferative activity against human HCT116 cells after 4 days by SRB method | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
6. | ALA2162326 | F | Antiproliferative activity against human MDA-MB-468 cells after 4 days by SRB method | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
7. | ALA2162329 | A | Cmax in Balb-C mouse plasma at 5 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
8. | ALA2162330 | A | Tmax in Balb-C mouse plasma at 5 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
9. | ALA2162338 | A | Cmax in Balb-C mouse kidney at 5 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
10. | ALA2162339 | A | Tmax in Balb-C mouse kidney at 5 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
11. | ALA2162340 | A | Ratio of drug level in kidney to plasma of Balb-C mouse at 5 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
12. | ALA2162341 | B | Inhibition of HSP90 in human BT474 cells assessed as depletion of Her2 protein level at 0.1 to 1 uM after 24 hrs by Western blot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA2162342 | B | Inhibition of HSP90 in human BT474 cells assessed as depletion of pHer2 protein level at 0.1 to 1 uM after 24 hrs by Western blot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
14. | ALA2162343 | B | Inhibition of HSP90 in human BT474 cells assessed as depletion of pAKT protein level at 0.1 to 1 uM after 24 hrs by Western blot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA2162498 | B | Inhibition of HSP90 in human BT474 cells assessed as depletion of AKT protein level at 0.1 to 1 uM after 24 hrs by Western blot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
16. | ALA2162499 | B | Inhibition of HSP90 in human BT474 cells assessed as induction of HSP70 at 0.1 to 1 uM after 24 hrs by Western blot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
17. | ALA2162500 | A | Intrinsic clearance in human liver microsomes assessed as UGT-mediated glucuronidation extraction ratio after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
18. | ALA2162501 | A | Intrinsic clearance in human liver microsomes assessed as UGT-mediated glucuronidation after 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
19. | ALA2162502 | A | AUC (0 to 2 hrs ) in Balb-C mouse plasma at 5 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
20. | ALA2162503 | A | AUC (0 to 2 hrs ) in Balb-C mouse kidney at 5 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature |