#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2161770	B	Binding affinity to Trypanosoma brucei MetRS at 100 uM by thermal shift assay	Trypanosoma brucei	30		assay format	Scientific Literature
2.	ALA2161885	B	Inhibition of Trypanosoma brucei MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-incubated for 15 mins before tRNA addition and measured after 120 mins by scintillation counting	Trypanosoma brucei	8		assay format	Scientific Literature
3.	ALA2161886	B	Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-incubated for 15 mins before tRNA addition and measured after 120 mins by scintillation counting	Homo sapiens	8		single protein format	Scientific Literature
4.	ALA2161887	B	Selectivity ratio of IC50 for human MetRS to IC50 for Trypanosoma brucei MetRS		8		assay format	Scientific Literature
5.	ALA2161888	F	Growth inhibition of Trypanosoma brucei brucei 427 blood stream forms after 48 hrs by alamar blue assay	Trypanosoma brucei brucei	8		organism-based format	Scientific Literature
6.	ALA2161889	A	Cytotoxicity against human CRL8155 cells incubated for 48 hrs by alamar blue assay	Homo sapiens	8		cell-based format	Scientific Literature
7.	ALA2161890	A	Cytotoxicity against human HepG2 cells incubated for 48 hrs by alamar blue assay	Homo sapiens	8		cell-based format	Scientific Literature
8.	ALA2161891	A	Permeability across MDCK2-MDR1 cells expressing MDR1 at 3 uM in presence of 2 uM P-gp inhibitor Elacridal by mass spectroscopy	Canis lupus familiaris	7		cell-based format	Scientific Literature
9.	ALA2161892	A	Permeability across MDCK2-MDR1 cells expressing MDR1 at 3 uM in absence of 2 uM P-gp inhibitor Elacridal by mass spectroscopy	Canis lupus familiaris	7		cell-based format	Scientific Literature
10.	ALA2161893	A	Drug level in Swiss Webster mouse brain at 5 mg/kg, ip after 60 mins by MS/MS method	Mus musculus	2		organism-based format	Scientific Literature
11.	ALA2161894	A	Cmax in mouse at 50 mg/kg, po administered as single dose measured over 6 hrs by MS/MS method	Mus musculus	3		organism-based format	Scientific Literature
12.	ALA2162442	A	Tmax in mouse at 50 mg/kg, po administered as single dose measured over 6 hrs by MS/MS method	Mus musculus	3		organism-based format	Scientific Literature
13.	ALA2162443	A	Half life in mouse at 50 mg/kg, po administered as single dose measured over 6 hrs by MS/MS method	Mus musculus	3		organism-based format	Scientific Literature
14.	ALA2162444	A	AUC in mouse at 50 mg/kg, po administered as single dose measured over 6 hrs by MS/MS method	Mus musculus	3		organism-based format	Scientific Literature
15.	ALA2162448	A	Plasma concentration in Swiss Webster mouse at 5 mg/kg, ip after 60 mins by MS/MS method	Mus musculus	1		organism-based format	Scientific Literature
16.	ALA2162449	A	Binding affinity to MDR1 expressed in MDCK2 cells assessed as absorptive quotient at at 3 uM in absence of 2 uM by mass spectroscopy		8		cell-based format	Scientific Literature