| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2163022 | B | Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 production | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA2163023 | B | Selectivity ratio of IC50 for PS2 gamma-secretase to IC50 for PS1 gamma-secretase | 9 | assay format | Scientific Literature | |||
| 3. | ALA2160914 | B | Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 production | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA2160915 | B | Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assay | 9 | assay format | Scientific Literature | |||
| 5. | ALA2160917 | F | Antialzheimer activity in transgenic CRND8 mouse assessed as increase of amyloid beta-40 level in plasma at 30 mg/kg, po after 3 hrs | Mus musculus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!