# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2162632 | Binding | Inhibition of human N-terminal His6-tagged Bcl2 isoform 2 expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BIM binding after 1 to 2 hrs by fluorescence polarization assay | Homo sapiens | 15 | ALA2157965 | assay format | Scientific Literature | |
2. | ALA2162633 | Binding | Inhibition of human N-terminal His8-tagged Bcl-XL expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BAK binding after 1 to 2 hrs by fluorescence polarization assay | Homo sapiens | 15 | ALA2157965 | assay format | Scientific Literature | |
3. | ALA2162634 | Binding | Inhibition of human N-terminal His8-tagged Mcl1 expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BID binding after 1 to 2 hrs by fluorescence polarization assay | Homo sapiens | 15 | ALA2157965 | assay format | Scientific Literature | |
4. | ALA2162635 | Functional | Antiproliferative activity against human NCI-H146 cells after 4 days by WST8 assay | Homo sapiens | 15 | ALA2157965 | cell-based format | Scientific Literature | |
5. | ALA2162636 | Functional | Antiproliferative activity against human NCI-H1417 cells after 4 days by WST8 assay | Homo sapiens | 15 | ALA2157965 | cell-based format | Scientific Literature | |
6. | ALA2162637 | Functional | Antiproliferative activity against human NCI-H1963 cells after 4 days by WST8 assay | Homo sapiens | 15 | ALA2157965 | cell-based format | Scientific Literature | |
7. | ALA2329998 | Functional | Cytotoxicity against human NCI-H146 cells assessed as growth inhibition after 4 days by WST assay | Homo sapiens | 28 | ALA2321752 | cell-based format | Scientific Literature | |
8. | ALA2329999 | Binding | Binding affinity to BCL-XL (unknown origin) after 2 hrs by fluorescence polarization assay | Homo sapiens | 28 | ALA2321752 | single protein format | Scientific Literature | |
9. | ALA2330000 | Binding | Binding affinity to BCL2 (unknown origin) after 2 hrs by fluorescence polarization assay | Homo sapiens | 28 | ALA2321752 | single protein format | Scientific Literature |