# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2162632 | B | Inhibition of human N-terminal His6-tagged Bcl2 isoform 2 expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BIM binding after 1 to 2 hrs by fluorescence polarization assay | Homo sapiens | 15 | assay format | Scientific Literature | ||
2. | ALA2162633 | B | Inhibition of human N-terminal His8-tagged Bcl-XL expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BAK binding after 1 to 2 hrs by fluorescence polarization assay | Homo sapiens | 15 | assay format | Scientific Literature | ||
3. | ALA2162634 | B | Inhibition of human N-terminal His8-tagged Mcl1 expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BID binding after 1 to 2 hrs by fluorescence polarization assay | Homo sapiens | 15 | assay format | Scientific Literature | ||
4. | ALA2162635 | F | Antiproliferative activity against human NCI-H146 cells after 4 days by WST8 assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
5. | ALA2162636 | F | Antiproliferative activity against human NCI-H1417 cells after 4 days by WST8 assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
6. | ALA2162637 | F | Antiproliferative activity against human NCI-H1963 cells after 4 days by WST8 assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
7. | ALA2329998 | F | Cytotoxicity against human NCI-H146 cells assessed as growth inhibition after 4 days by WST assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
8. | ALA2329999 | B | Binding affinity to BCL-XL (unknown origin) after 2 hrs by fluorescence polarization assay | Homo sapiens | 28 | single protein format | Scientific Literature | ||
9. | ALA2330000 | B | Binding affinity to BCL2 (unknown origin) after 2 hrs by fluorescence polarization assay | Homo sapiens | 28 | single protein format | Scientific Literature |