# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2161819 | Binding | Inhibition of LYP-mediated TCR signaling in C305 antibody stimulated mouse Ptpn22+/+ T cells assessed as increase in Src Y416 phosphorylation at 50 uM by Western blotting relative to untreated control | Mus musculus | 28 | ALA2157931 | cell-based format | Scientific Literature | |
2. | ALA2161820 | Binding | Inhibition of LYP-mediated TCR signaling in C305 antibody stimulated human Jurkat T cells expressing SV40 large T antigen assessed as increase in pSRC Y416 dephosphorylation at 50 uM by Western blotting relative to untreated control | Homo sapiens | 28 | ALA2157931 | cell-based format | Scientific Literature | |
3. | ALA2161822 | Binding | Selectivity ratio of IC50 for HePTP to IC50 for LYP | 28 | ALA2157931 | assay format | Scientific Literature | ||
4. | ALA2161823 | Binding | Selectivity ratio of IC50 for PTP-PEST to IC50 for LYP | 33 | ALA2157931 | assay format | Scientific Literature | ||
5. | ALA2161837 | Binding | Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate | 45 | ALA2157931 | assay format | Scientific Literature | ||
6. | ALA2161840 | Binding | Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate | 5 | ALA2157931 | assay format | Scientific Literature | ||
7. | ALA2161973 | Binding | Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate | 6 | ALA2157931 | assay format | Scientific Literature |