# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2161819 | B | Inhibition of LYP-mediated TCR signaling in C305 antibody stimulated mouse Ptpn22+/+ T cells assessed as increase in Src Y416 phosphorylation at 50 uM by Western blotting relative to untreated control | Mus musculus | 28 | ALA2157931 | cell-based format | Scientific Literature | |
2. | ALA2161820 | B | Inhibition of LYP-mediated TCR signaling in C305 antibody stimulated human Jurkat T cells expressing SV40 large T antigen assessed as increase in pSRC Y416 dephosphorylation at 50 uM by Western blotting relative to untreated control | Homo sapiens | 28 | ALA2157931 | cell-based format | Scientific Literature | |
3. | ALA2161823 | B | Selectivity ratio of IC50 for PTP-PEST to IC50 for LYP | 33 | ALA2157931 | assay format | Scientific Literature | ||
4. | ALA2161837 | B | Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate | 45 | ALA2157931 | assay format | Scientific Literature | ||
5. | ALA2161972 | B | Inhibition of HePTP expressed in Escherichia coli BL21 using pNPP substrate | 17 | ALA2157931 | assay format | Scientific Literature |