# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2162663 | F | Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assay | Mus musculus | 7 | ALA2157999 | cell-based format | Scientific Literature | |
2. | ALA2162665 | A | Cytotoxicity against HUVEC up to 10 uM after 24 hrs by WST-1 assay | Homo sapiens | 7 | ALA2157999 | cell-based format | Scientific Literature | |
3. | ALA2162666 | A | Cytotoxicity against HUVEC after 24 hrs by WST-1 assay | Homo sapiens | 2 | ALA2157999 | cell-based format | Scientific Literature | |
4. | ALA2162667 | A | Ratio of compound IC50 to SAG IC50 for HUVEC | Homo sapiens | 1 | ALA2157999 | cell-based format | Scientific Literature | |
5. | ALA2162668 | B | Activation of Shh pathway in human foreskin fibroblasts assessed as increase in VEGF expression after 48 hrs by ELISA | Homo sapiens | 4 | ALA2157999 | assay format | Scientific Literature | |
6. | ALA2162669 | B | Activation of Shh pathway in human foreskin fibroblasts assessed as increase in VEGF expression at 0.1 to 1 uM after 48 hrs by ELISA relative to control | Homo sapiens | 4 | ALA2157999 | assay format | Scientific Literature | |
7. | ALA2162671 | B | Activation of Shh pathway in human foreskin fibroblasts assessed as induction of maximum VEGF expression at 1 uM after 48 hrs by ELISA relative to control | Homo sapiens | 3 | ALA2157999 | assay format | Scientific Literature | |
8. | ALA2162672 | F | Induction of HUVEC proliferation after 48 hrs by BrdU-incorporation assay | Homo sapiens | 32 | ALA2157999 | cell-based format | Scientific Literature | |
9. | ALA2162673 | F | Induction of angiogenesis in HUVEC assessed as formation of cell sprouts after 48 hrs by BrdU incorporation assay | Homo sapiens | 32 | ALA2157999 | cell-based format | Scientific Literature |