# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2167928 | F | Antiangiogenic effect in CB57BL/6 mouse microvascular choroid explants assessed as choroid sprouting at 10'-7 M after 4 days (Rvb = 53%) | Mus musculus | 7 | assay format | Scientific Literature | ||
2. | ALA2167929 | B | Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method | 53 | cell-based format | Scientific Literature | |||
3. | ALA2167930 | B | Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry | Rattus norvegicus | 53 | cell membrane format | Scientific Literature | ||
4. | ALA4020662 | B | Modulation of CD36 in mouse RAW1 cells assessed as inhibition of R-FSL1-induced NO over production at 1 uM preincubated for 1 hr followed by overnight R-FSL1 stimulation by DAN-fluorescence assay relative to control | Mus musculus | 24 | cell-based format | Scientific Literature | ||
5. | ALA4020663 | B | Modulation of CD36 in mouse J774A.1 cells assessed as inhibition of R-FSL1-induced NO over production at 1 uM preincubated for 1 hr followed by overnight R-FSL1 stimulation by DAN-fluorescence assay relative to control | Mus musculus | 24 | cell-based format | Scientific Literature | ||
6. | ALA4020664 | B | Inhibition of photoactivatable [125I]-Tyr-Bpa-Ala-hexarelin binding to CD36 in Sprague-Dawley rat heart membranes after 60 mins by SDS-PAGE analysis | Rattus norvegicus | 15 | cell membrane format | Scientific Literature | ||
7. | ALA4020665 | B | Inhibition of photoactivatable [125I]-Tyr-Bpa-Ala-hexarelin binding to CD36 in Sprague-Dawley rat heart membranes after 60 mins by SDS-PAGE analysis relative to H-His-D-Trp-Ala-aza(3-hydroxy)Phe-D-Phe-Lys-NH2 | Rattus norvegicus | 14 | cell membrane format | Scientific Literature | ||
8. | ALA4020666 | F | Anti-angiogenic activity in mouse sclera/choroid/retinal pigment epithelium complex assessed as reduction in microvascular sprouting at 1 uM after 24 hrs by microscopic analysis | Mus musculus | 12 | assay format | Scientific Literature | ||
9. | ALA4418204 | B | Displacement of [125]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat heart membranes incubated for 60 mins | Rattus norvegicus | 23 | cell membrane format | Patent Bioactivity Data | ||
10. | ALA4418205 | F | Inhibition of R-FSL-1-induced TNFalpha production in mouse RAW264.7 cells at 10 uM pre-incubated for 30 mins before R-FSL-1 stimulation for 4 hrs by ELISA | Mus musculus | 8 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4418206 | F | Inhibition of R-FSL-1-induced CCL2 production in mouse RAW264.7 cells at 10 uM pre-incubated for 30 mins before R-FSL-1 stimulation for 4 hrs by ELISA | Mus musculus | 8 | cell-based format | Patent Bioactivity Data | ||
12. | ALA4418207 | F | Anti-atherosclerotic activity in atherogenic diet fed apoE-/- mouse assessed as reduction in aortic lesions at 300 nmol/kg, sc dosed daily for 8 weeks from from 12 weeks of age relative to control | Mus musculus | 6 | organism-based format | Patent Bioactivity Data | ||
13. | ALA4476896 | B | Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins and followed by UV irradiation and measured after 15 mins by radioligand binding assay | Rattus norvegicus | 34 | assay format | Patent Bioactivity Data | ||
14. | ALA4476897 | B | Displacement of [125I]-ghrelin (1 to 28 residues) from human GHS-R1a expressed in pig LLC-PK1 cell membranes by LKB gamma counter method | Homo sapiens | 48 | cell-based format | Patent Bioactivity Data | ||
15. | ALA4476898 | F | Inhibition of vascular sprouting in CD36+/+ C57BL/6 mouse aortic rings exposed on day 4 to 6 | Mus musculus | 1 | tissue-based format | Patent Bioactivity Data | ||
16. | ALA4476899 | F | Inhibition of vascular sprouting in CD36-/- C57BL/6 mouse aortic rings exposed on day 4 to 6 | Mus musculus | 1 | tissue-based format | Patent Bioactivity Data | ||
17. | ALA4476900 | F | Inhibition of choroidal neovascularization in CD36+/+ C57BL/6 mouse model of FITC-conjugated dextran infusion following laser-induced posterior retinal injury administered in to vitreous tissue | Mus musculus | 1 | organism-based format | Patent Bioactivity Data | ||
18. | ALA4476901 | F | Inhibition of choroidal neovascularization in CD36-/- C57BL/6 mouse model of FITC-conjugated dextran infusion following laser-induced posterior retinal injury administered in to vitreous tissue | Mus musculus | 1 | organism-based format | Patent Bioactivity Data |