# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2167731 | B | Inhibition of human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as reduction in GABA-induced current response at >100 uM by two-electrode voltage clamp assay relative to untreated control | Homo sapiens | 1 | ALA2163302 | cell-based format | Scientific Literature | |
2. | ALA2167734 | B | Inhibition of human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as reduction in 1 mM GABA-induced current response at 80 uM by two-electrode voltage clamp assay relative to untreated control | Homo sapiens | 1 | ALA2163302 | cell-based format | Scientific Literature | |
3. | ALA2167735 | B | Inhibition of [3H]R-(-)-14-induced receptor photolabeling at human FLAG-tagged alpha1 GABA A receptor expressed in HEK293S cells relative to untreated control | Homo sapiens | 2 | ALA2163302 | cell-based format | Scientific Literature | |
4. | ALA2167736 | B | Inhibition of [3H]R-(-)-14-induced receptor photolabeling at human FLAG-tagged beta3 GABA A receptor expressed in HEK293S cells relative to untreated control | Homo sapiens | 2 | ALA2163302 | cell-based format | Scientific Literature | |
5. | ALA2168415 | B | Displacement of [3H]R-(-)-14 from human FLAG-tagged alpha1 GABA A receptor expressed in HEK293S cells | Homo sapiens | 3 | ALA2163302 | cell-based format | Scientific Literature | |
6. | ALA2168416 | B | Displacement of [3H]R-(-)-14 from human FLAG-tagged beta3 GABA A receptor expressed in HEK293S cells | Homo sapiens | 3 | ALA2163302 | cell-based format | Scientific Literature | |
7. | ALA2168418 | B | Activation of human alpha1beta3gamma2L GABA A receptor expressed in HEK293 cells assessed as increase in [3H]muscimol binding by scintillation counting assay | Homo sapiens | 2 | ALA2163302 | cell-based format | Scientific Literature | |
8. | ALA2168419 | F | Agonist activity at human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as increase in current response by two-electrode voltage clamp assay relative to GABA | Homo sapiens | 2 | ALA2163302 | cell-based format | Scientific Literature | |
9. | ALA2168420 | F | Agonist activity at human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as increase in current response by two-electrode voltage clamp assay | Homo sapiens | 2 | ALA2163302 | cell-based format | Scientific Literature | |
10. | ALA2168643 | B | Activation of human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as potentiation of 10 uM GABA-induced current response at 80 uM by two-electrode voltage clamp assay relative to untreated control | Homo sapiens | 1 | ALA2163302 | cell-based format | Scientific Literature | |
11. | ALA2168645 | B | Activation of human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced current response at 100 uM by two-electrode voltage clamp assay relative to untreated control | Homo sapiens | 1 | ALA2163302 | cell-based format | Scientific Literature | |
12. | ALA2168646 | B | Activation of human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced current response at 30 uM by two-electrode voltage clamp assay relative to untreated control | Homo sapiens | 1 | ALA2163302 | cell-based format | Scientific Literature | |
13. | ALA2168648 | B | Activation of human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced current response at 80 uM by two-electrode voltage clamp assay relative to untreated control | Homo sapiens | 1 | ALA2163302 | cell-based format | Scientific Literature | |
14. | ALA2168649 | F | Anesthetic activity in Xenopus laevis tadpoles assessed as loss of of righting reflexes | Xenopus laevis | 3 | ALA2163302 | organism-based format | Scientific Literature |