# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2169093 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL10 release at 20 uM incubated for 4 to 40 hrs by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
2. | ALA2169094 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL8 release at 20 uM incubated for 4 to 40 hrs by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
3. | ALA2169095 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL-12p70 release at 20 uM by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
4. | ALA2169096 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL6 release at 20 uM by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
5. | ALA2169098 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL-1beta release at 20 uM by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
6. | ALA2169099 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL10 release at 0.2 to 200 uM incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
7. | ALA2169100 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL8 release at 0.2 to 200 uM incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
8. | ALA2169101 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced TNFalpha release incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
9. | ALA2169102 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL6 release incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
10. | ALA2169103 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL-1beta release incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 2 | ALA2163344 | cell-based format | Scientific Literature | |
11. | ALA2169104 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced TNFalpha release at 20 uM incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 7 | ALA2163344 | cell-based format | Scientific Literature | |
12. | ALA2169105 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL-12p70 release at 20 uM incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature | |
13. | ALA2169106 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL10 release at 20 uM incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature | |
14. | ALA2169107 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL6 release at 20 uM incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 7 | ALA2163344 | cell-based format | Scientific Literature | |
15. | ALA2169108 | F | Immunomodulatory activity in human PBMCs assessed as increase in PMA/ionomycin-induced IL-1beta release at 20 uM incubated for 18 hrs by multiplexed cytokine assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature | |
16. | ALA2169109 | A | Cytotoxicity against human PBMCs assessed as residual metabolic activity at 20 uM in presence of PMA and ionomycin after 18 hrs by MTS assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature | |
17. | ALA2169110 | A | Cytotoxicity against human PBMCs assessed as residual metabolic activity at 20 uM after 18 hrs by MTS assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature | |
18. | ALA2169111 | F | Agonist activity at human NOD1 expressed in Ramos blue cells assessed as stimulation of NF-kB/AP-1 activity at 20 uM incubated for 18 hrs using quanti blue assay based SEAP reporter gene assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature | |
19. | ALA2169112 | F | Agonist activity at human TLR9 expressed in Ramos blue cells assessed as stimulation of NF-kB/AP-1 activity at 20 uM incubated for 18 hrs using quanti blue assay based SEAP reporter gene assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature | |
20. | ALA2166307 | F | Agonist activity at human TLR7 expressed in Ramos blue cells assessed as stimulation of NF-kB/AP-1 activity at 20 uM incubated for 18 hrs using quanti blue assay based SEAP reporter gene assay | Homo sapiens | 8 | ALA2163344 | cell-based format | Scientific Literature |